Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13266634
rs13266634
C 1.000 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE A non-synonymous polymorphism (R325W) in its gene is associated with Type-2 diabetes. 30710592

2019

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE A specific genetic variant, rs13266634 (c.973C>T; p.ARG325TRP) in zinc transporter SLC30A8/ZnT8, is associated with protection against Type-2 Diabetes, suggesting it may be actionable for predicting and preventing POHG. 31220282

2019

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE The current study demonstrated a modest but significant effect of SLC30A8 (rs13266634) polymorphisms on T2D predisposition. 31823921

2019

dbSNP: rs13266634
rs13266634
C 1.000 GeneticVariation GWASCAT Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 29632382

2018

dbSNP: rs13266634
rs13266634
C 1.000 GeneticVariation GWASCAT Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. 29358691

2018

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE A common variant W325R in the C-terminal domain (CTD) increases the risk to develop type 2 diabetes and affects autoantibody specificity in type 1 diabetes. 29430817

2018

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE A total of 556 healthy controls and 413 T2DM patients were genotyped for ZnT8 Arg325Trp polymorphism confirming the association of Arg-325 variant with an increased T2DM risk (OR = 1.35 95% C.I: 1.10-1.66; p = 0.0044). 30142362

2018

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE <b>Conclusion:</b> The present meta-analysis demonstrated that <i>SLC30A8</i> rs13266634 was a potential risk factor for T2DM, and more studies should be performed to confirm the association between rs13266634 polymorphism and IGR. 30319545

2018

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE We replicated the association of T2D risk with I<i>GF2BP</i> rs4402960 and detected novel associations with <i>TERT</i> rs2735940 and rs2736098. 29410390

2018

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE The aim of this study was to analyse the association between PPARG rs1801282, PPARGC1A rs8192678, VEGFA rs2010963, ADRA2A rs553668, KCNQ1 rs2237892, SIRT1 rs7896005, IGF2BP2 rs4402960, and UCP3 rs3781907 single nucleotide variants (SNVs) with T2D and metabolic traits in a case-control study of a population from Mexico City. 29800730

2018

dbSNP: rs13266634
rs13266634
T 1.000 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590

2017

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE ZnT8 null mice have a mild phenotype with a slight decrease in glucose tolerance, whereas patients with the ZnT8 R325W polymorphism (rs13266634) have decreased proinsulin staining and susceptibility to T2DM. 27899481

2017

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Statistically significant associations of T2D with five of the tested single nucleotide polymorphisms (SNPs) (<i>TCF7L2</i> rs7901695, <i>FTO</i> rs8050136, <i>HHEX</i> rs5015480, <i>SLC30A8</i> rs13266634 and <i>IGF2BP2</i> rs4402960) were observed in this study population. 28067832

2017

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE After excluding four SNPs due to Hardy-Weinberg disequilibrium, significant associations in age-matched cohorts were found betweenT2DM and the following SNPs: rs9939609 (FTO), rs13266634 (SLC30A8), rs7961581 (TSPAN8/LGR5), and rs1799883 (FABP2). 28738793

2017

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE The non-synonymous single nucleotide polymorphism (SNP) rs13266634 in human zinc transporter 8, ZnT8 (SLC30A8), leads to a R325 variant, which is associated with an increased risk of developing Type 2 Diabetes (T2D). 28965566

2017

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE The solute carrier family 30 member 8 gene (<i>SLC30A8</i>) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in <i>SLC30A8</i> is associated with an increased risk of type 2 diabetes (T2D). 29093761

2017

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE Statistically significant associations of T2D with five of the tested single nucleotide polymorphisms (SNPs) (<i>TCF7L2</i> rs7901695, <i>FTO</i> rs8050136, <i>HHEX</i> rs5015480, <i>SLC30A8</i> rs13266634 and <i>IGF2BP2</i> rs4402960) were observed in this study population. 28067832

2017

dbSNP: rs13266634
rs13266634
C 1.000 GeneticVariation GWASCAT Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. 27189021

2016

dbSNP: rs13266634
rs13266634
C 1.000 GeneticVariation GWASCAT Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. 26818947

2016

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Although previous meta-analyses have shown that this association was only found in Asian and European groups, and not in African populations, our analysis revealed the deleterious effect of SLC30A8 rs13266634 on T2DM in an African population when stratified by ethnicity under additive model even with a small number of studies. 26832344

2016

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE The R325W C-allele were more frequent in women with GDM compared to in controls (OR 1.47, 95 % CI 1.16-1.88, p = 0.0018) but not significantly increased in women with GDM and postpartum development of type 2 diabetes. 27003436

2016

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE We confirm the association of TCF7L2 (rs7903146) and SLC30A8 (rs13266634) with T2D. 27310578

2016

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE We assessed the interaction between type 2 diabetes-associated SLC30A8 rs13266634 and gestational weight gain on 1-5 years of postpartum glycemic changes in 1,071 women with prior GDM in a longitudinal study. 27600066

2016

dbSNP: rs4402960
rs4402960
T 1.000 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016