Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12523822
rs12523822
0.710 GeneticVariation GWASCAT Within ethnic group meta-analysis of discovery GWAS and replication set results identified genome-wide significant evidence for association between DKD and rs12523822 on chromosome 6q25.2 in American Indians (P = 5.74x10-9). 26305897

2015

dbSNP: rs12523822
rs12523822
0.710 GeneticVariation BEFREE Within ethnic group meta-analysis of discovery GWAS and replication set results identified genome-wide significant evidence for association between DKD and rs12523822 on chromosome 6q25.2 in American Indians (P = 5.74x10-9). 26305897

2015

dbSNP: rs955333
rs955333
0.710 GeneticVariation GWASCAT Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND). 26305897

2015

dbSNP: rs955333
rs955333
0.710 GeneticVariation BEFREE <i>Background</i>.Genome-wide association studies found rs955333 located in 6q25.2 was associated with diabetic kidney disease in multiple ethnic populations, including European Americans, African Americans, and Mexican Americans. 28401168

2017

dbSNP: rs9942471
rs9942471
0.710 GeneticVariation BEFREE Analysis of specific DKD phenotypes identified a novel signal near <i>GABRR1</i> (rs9942471, <i>P</i> = 4.5 × 10<sup>-8</sup>) associated with microalbuminuria in European T2D case subjects. 29703844

2018

dbSNP: rs9942471
rs9942471
A 0.710 GeneticVariation GWASCAT Analysis of specific DKD phenotypes identified a novel signal near <i>GABRR1</i> (rs9942471, <i>P</i> = 4.5 × 10<sup>-8</sup>) associated with microalbuminuria in European T2D case subjects. 29703844

2018

dbSNP: rs10952362
rs10952362
C 0.700 GeneticVariation GWASCAT Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND). 26305897

2015

dbSNP: rs1249910
rs1249910
0.700 GeneticVariation GWASCAT Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND). 26305897

2015

dbSNP: rs16996381
rs16996381
0.700 GeneticVariation GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874

2011

dbSNP: rs1800764
rs1800764
0.020 GeneticVariation BEFREE In the case-control analysis, the rs1800764-C, rs4311-T, Insertion/deletion (I/D or rs1799752)-D, rs4366-G, and rs12449782-G alleles were associated with an increased risk for DN, homogeneously across populations, with allelic odds ratios of 1.11 (95% confidence interval 1.00 to 1.22), 1.18 (1.04 to 1.33), 1.13 (1.02 to 1.23), 1.10 (0.99 to 1.20), and 1.12 (1.01 to 1.23), respectively. 17376814

2007

dbSNP: rs1800764
rs1800764
0.020 GeneticVariation BEFREE Higher frequency of rs1799752 and rs1800764 homozygous mutant genotypes was seen in DN compared to DWN patients. 19787680

2009

dbSNP: rs1866813
rs1866813
0.020 GeneticVariation BEFREE A genetic variant, rs1866813, in the noncoding region at 3q22 was associated with increased risk of DN (overall p = 7.07 x 10(-6), combined odds ratio [OR] of the allele = 1.33). 19084216

2009

dbSNP: rs1866813
rs1866813
0.020 GeneticVariation BEFREE We have previously reported genetic association of a single nucleotide polymorphism (SNP), rs1866813, at 3q locus with increased risk of diabetic nephropathy (DN). 23441190

2013

dbSNP: rs10255208
rs10255208
0.010 GeneticVariation BEFREE The rs741301-G allele and the rs10255208-GG genotype, gene-environment interaction between rs741301 and alcohol drinking were all associated with increased DN risk. 31798690

2019

dbSNP: rs10811661
rs10811661
0.010 GeneticVariation BEFREE A SNP predisposing to type 2 diabetes mellitus, rs10811661 near CDKN2A/B, is associated with diabetic nephropathy in patients with type 1 diabetes mellitus. 22643932

2012

dbSNP: rs11646213
rs11646213
0.010 GeneticVariation BEFREE In SURGENE, rs11646213 [hazard ratio (HR) 1.69; 95% CI 1.01-2.71; P = 0.04] and rs3865188 (HR 0.74; 95% CI 0.55-0.99; P = 0.04) were associated with risk of renal events (defined as progression to more severe DN stages). 28499019

2017

dbSNP: rs11886047
rs11886047
0.010 GeneticVariation BEFREE A single marker, rs11886047, located upstream of the PLEKHH2 promoter was associated with DN by TdT in the case trios (P = 0.0307), and there was a increase of heterozygous genotypes in cases, relative to controls, from the 601 case and 577 control GoKinD singleton case/control population (P = 0.00256). 18752002

2008

dbSNP: rs12449782
rs12449782
0.010 GeneticVariation BEFREE Haplotype analysis further demonstrated that the haplotype defined by the D, rs4366_G and rs12449782_G alleles was associated with a greater risk for DN. 17376814

2007

dbSNP: rs1253192
rs1253192
0.010 GeneticVariation BEFREE A logistic regression model including collection centre, duration of diabetes, and average HbA1c as covariates highlighted three SNPs in GSK3B (rs17810235, rs17471, rs334543), two in DAAM1 (rs1253192, rs1252906) and one in NFAT5 (rs17297207) as being significantly (P < 0.05) associated with DN, however these SNPs did not remain significant after correction for multiple testing. 23777469

2013

dbSNP: rs16835198
rs16835198
0.010 GeneticVariation BEFREE Association of irisin and FNDC5 rs16835198 G>T gene polymorphism with type 2 diabetes mellitus and diabetic nephropathy. An Egyptian pilot study. 28479383

2017

dbSNP: rs17300593
rs17300593
0.010 GeneticVariation BEFREE Adiponectin rs2241766T/G and rs17300593G/A rather than rs1501299G/T and rs266729C/G polymorphisms were associated with the risk of DN in T2DM, especially in the Caucasian population. 24825737

2015

dbSNP: rs1942872
rs1942872
0.010 GeneticVariation BEFREE Here we investigated the association of POL1-nearby variant rs488846, MALT1-nearby variant rs2874116, MC4R-nearby variant rs1942872, PHLPP rs9958800 and DSEL-nearby variant rs9966483 single nucleotide polymorphisms (SNPs) in the 18q region, previously linked with DN in African-Americans, with T2DM in (North African) Tunisian subjects, followed by their association with DN, which was performed subsequent to the analysis of the association with T2DM. 23727064

2013

dbSNP: rs2874116
rs2874116
0.010 GeneticVariation BEFREE Here we investigated the association of POL1-nearby variant rs488846, MALT1-nearby variant rs2874116, MC4R-nearby variant rs1942872, PHLPP rs9958800 and DSEL-nearby variant rs9966483 single nucleotide polymorphisms (SNPs) in the 18q region, previously linked with DN in African-Americans, with T2DM in (North African) Tunisian subjects, followed by their association with DN, which was performed subsequent to the analysis of the association with T2DM. 23727064

2013

dbSNP: rs334543
rs334543
0.010 GeneticVariation BEFREE A logistic regression model including collection centre, duration of diabetes, and average HbA1c as covariates highlighted three SNPs in GSK3B (rs17810235, rs17471, rs334543), two in DAAM1 (rs1253192, rs1252906) and one in NFAT5 (rs17297207) as being significantly (P < 0.05) associated with DN, however these SNPs did not remain significant after correction for multiple testing. 23777469

2013

dbSNP: rs3865188
rs3865188
0.010 GeneticVariation BEFREE In SURGENE, rs11646213 [hazard ratio (HR) 1.69; 95% CI 1.01-2.71; P = 0.04] and rs3865188 (HR 0.74; 95% CI 0.55-0.99; P = 0.04) were associated with risk of renal events (defined as progression to more severe DN stages). 28499019

2017