rs12523822
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
Within ethnic group meta-analysis of discovery GWAS and replication set results identified genome-wide significant evidence for association between DKD and rs12523822 on chromosome 6q25.2 in American Indians (P = 5.74x10-9).
|
26305897 |
2015 |
rs12523822
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Within ethnic group meta-analysis of discovery GWAS and replication set results identified genome-wide significant evidence for association between DKD and rs12523822 on chromosome 6q25.2 in American Indians (P = 5.74x10-9).
|
26305897 |
2015 |
rs955333
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
|
26305897 |
2015 |
rs955333
|
|
|
0.710 |
GeneticVariation |
BEFREE |
<i>Background</i>.Genome-wide association studies found rs955333 located in 6q25.2 was associated with diabetic kidney disease in multiple ethnic populations, including European Americans, African Americans, and Mexican Americans.
|
28401168 |
2017 |
rs9942471
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Analysis of specific DKD phenotypes identified a novel signal near <i>GABRR1</i> (rs9942471, <i>P</i> = 4.5 × 10<sup>-8</sup>) associated with microalbuminuria in European T2D case subjects.
|
29703844 |
2018 |
rs9942471
|
|
A |
0.710 |
GeneticVariation |
GWASCAT |
Analysis of specific DKD phenotypes identified a novel signal near <i>GABRR1</i> (rs9942471, <i>P</i> = 4.5 × 10<sup>-8</sup>) associated with microalbuminuria in European T2D case subjects.
|
29703844 |
2018 |
rs10952362
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
|
26305897 |
2015 |
rs1249910
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
|
26305897 |
2015 |
rs16996381
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study for diabetic nephropathy genes in African Americans.
|
21150874 |
2011 |
rs1800764
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In the case-control analysis, the rs1800764-C, rs4311-T, Insertion/deletion (I/D or rs1799752)-D, rs4366-G, and rs12449782-G alleles were associated with an increased risk for DN, homogeneously across populations, with allelic odds ratios of 1.11 (95% confidence interval 1.00 to 1.22), 1.18 (1.04 to 1.33), 1.13 (1.02 to 1.23), 1.10 (0.99 to 1.20), and 1.12 (1.01 to 1.23), respectively.
|
17376814 |
2007 |
rs1800764
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Higher frequency of rs1799752 and rs1800764 homozygous mutant genotypes was seen in DN compared to DWN patients.
|
19787680 |
2009 |
rs1866813
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A genetic variant, rs1866813, in the noncoding region at 3q22 was associated with increased risk of DN (overall p = 7.07 x 10(-6), combined odds ratio [OR] of the allele = 1.33).
|
19084216 |
2009 |
rs1866813
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have previously reported genetic association of a single nucleotide polymorphism (SNP), rs1866813, at 3q locus with increased risk of diabetic nephropathy (DN).
|
23441190 |
2013 |
rs10255208
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs741301-G allele and the rs10255208-GG genotype, gene-environment interaction between rs741301 and alcohol drinking were all associated with increased DN risk.
|
31798690 |
2019 |
rs10811661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A SNP predisposing to type 2 diabetes mellitus, rs10811661 near CDKN2A/B, is associated with diabetic nephropathy in patients with type 1 diabetes mellitus.
|
22643932 |
2012 |
rs11646213
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In SURGENE, rs11646213 [hazard ratio (HR) 1.69; 95% CI 1.01-2.71; P = 0.04] and rs3865188 (HR 0.74; 95% CI 0.55-0.99; P = 0.04) were associated with risk of renal events (defined as progression to more severe DN stages).
|
28499019 |
2017 |
rs11886047
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single marker, rs11886047, located upstream of the PLEKHH2 promoter was associated with DN by TdT in the case trios (P = 0.0307), and there was a increase of heterozygous genotypes in cases, relative to controls, from the 601 case and 577 control GoKinD singleton case/control population (P = 0.00256).
|
18752002 |
2008 |
rs12449782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis further demonstrated that the haplotype defined by the D, rs4366_G and rs12449782_G alleles was associated with a greater risk for DN.
|
17376814 |
2007 |
rs1253192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A logistic regression model including collection centre, duration of diabetes, and average HbA1c as covariates highlighted three SNPs in GSK3B (rs17810235, rs17471, rs334543), two in DAAM1 (rs1253192, rs1252906) and one in NFAT5 (rs17297207) as being significantly (P < 0.05) associated with DN, however these SNPs did not remain significant after correction for multiple testing.
|
23777469 |
2013 |
rs16835198
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of irisin and FNDC5 rs16835198 G>T gene polymorphism with type 2 diabetes mellitus and diabetic nephropathy. An Egyptian pilot study.
|
28479383 |
2017 |
rs17300593
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Adiponectin rs2241766T/G and rs17300593G/A rather than rs1501299G/T and rs266729C/G polymorphisms were associated with the risk of DN in T2DM, especially in the Caucasian population.
|
24825737 |
2015 |
rs1942872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we investigated the association of POL1-nearby variant rs488846, MALT1-nearby variant rs2874116, MC4R-nearby variant rs1942872, PHLPP rs9958800 and DSEL-nearby variant rs9966483 single nucleotide polymorphisms (SNPs) in the 18q region, previously linked with DN in African-Americans, with T2DM in (North African) Tunisian subjects, followed by their association with DN, which was performed subsequent to the analysis of the association with T2DM.
|
23727064 |
2013 |
rs2874116
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we investigated the association of POL1-nearby variant rs488846, MALT1-nearby variant rs2874116, MC4R-nearby variant rs1942872, PHLPP rs9958800 and DSEL-nearby variant rs9966483 single nucleotide polymorphisms (SNPs) in the 18q region, previously linked with DN in African-Americans, with T2DM in (North African) Tunisian subjects, followed by their association with DN, which was performed subsequent to the analysis of the association with T2DM.
|
23727064 |
2013 |
rs334543
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A logistic regression model including collection centre, duration of diabetes, and average HbA1c as covariates highlighted three SNPs in GSK3B (rs17810235, rs17471, rs334543), two in DAAM1 (rs1253192, rs1252906) and one in NFAT5 (rs17297207) as being significantly (P < 0.05) associated with DN, however these SNPs did not remain significant after correction for multiple testing.
|
23777469 |
2013 |
rs3865188
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In SURGENE, rs11646213 [hazard ratio (HR) 1.69; 95% CI 1.01-2.71; P = 0.04] and rs3865188 (HR 0.74; 95% CI 0.55-0.99; P = 0.04) were associated with risk of renal events (defined as progression to more severe DN stages).
|
28499019 |
2017 |