We found that the C allele of rs1800625 and the T allele of rs184003 within <i>RAGE</i> gene, interaction between rs1800625 and smoking were all associated with increased DN risk.
A meta-analysis was performed to assess the associations of the receptor for advanced glycation end products (RAGE) gene polymorphisms [Gly82Ser (rs2070600), 1704G/T (rs184003), 429T/C (rs1800625)] with type 2 diabetes mellitus (T2DM), diabetic retinopathy (DR) and diabetic nephropathy (DN).