Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.070 | GeneticVariation | BEFREE | We found that Gly82Ser in RAGE showed significant association with DR. More studies with larger sample sizes that control for important risk factors, such as duration of diabetes, are needed to validate our findings. | 27684793 | 2016 |
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0.070 | GeneticVariation | BEFREE | The findings suggest that the G82S polymorphism in the RAGE gene is associated with DR risk, and G82S was associated with circulating levels of sRAGE. | 24303504 | 2013 |
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0.070 | GeneticVariation | BEFREE | Otherwise, the RAGE Gly82Ser polymorphism might be considered a significant risk for DR in Asian populations. | 22354095 | 2012 |
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0.070 | GeneticVariation | BEFREE | Z+2 allele of ALR2, 13-repeat genotype of iNOS, 15-repeat genotype of TNF-β, genes were associated with susceptibility to DR. Gly82Ser polymorphisms of the RAGE gene were not associated with DR in the present study. | 21067489 | 2010 |
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0.070 | GeneticVariation | BEFREE | Among the nine loci (15 polymorphisms) screened, SNP rs2070600 (G82S) in the RAGE gene, showed significant association with DR (allelic P = 0.016, dominant model P = 0.012), compared to DNR. | 21067572 | 2010 |
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0.070 | GeneticVariation | BEFREE | This study confirms significant association of one polymorphism only (rs2070600 in RAGE) with DR in an Indian population which had T2DM. | 21067572 | 2010 |
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0.070 | GeneticVariation | BEFREE | G82S polymorphism in the RAGE gene is associated with DR and G-A haplotype containing 1704G and 82S allele might be a genetic marker of DR in Chinese T2DM patients. | 19542745 | 2009 |
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0.070 | GeneticVariation | BEFREE | Association of Gly82Ser polymorphism in the RAGE gene with diabetic retinopathy in type II diabetic Asian Indian patients. | 12477623 | 2003 |