rs56372821
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study implicates CHRNA2 in cannabis use disorder.
|
31209380 |
2019 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
However, whether the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism participates in the childhood-abuse influenced schizophrenic symptoms remains unclear.
|
29595641 |
2018 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
However, whether the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism participates in the childhood-abuse influenced schizophrenic symptoms remains unclear.
|
29595641 |
2018 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Significant four-way interactions were found for BDNF Val66Met × 5-HTTLPR×MAOA-uVNTR × family conflicts and for BDNF Val66Met × 5-HTTLPR×MAOA-uVNTR × sexual abuse.
|
25522433 |
2014 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Significant four-way interactions were found for BDNF Val66Met × 5-HTTLPR×MAOA-uVNTR × family conflicts and for BDNF Val66Met × 5-HTTLPR×MAOA-uVNTR × sexual abuse.
|
25522433 |
2014 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our data demonstrate that in patients with psychoses, met carriers of the BDNF val66met with high level of childhood abuse have more cognitive and brain abnormalities than all other groups.
|
23876786 |
2013 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our data demonstrate that in patients with psychoses, met carriers of the BDNF val66met with high level of childhood abuse have more cognitive and brain abnormalities than all other groups.
|
23876786 |
2013 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, BDNF val(66)met has a significant impact on hippocampal volume independently of childhood abuse and psychiatric status.
|
22832736 |
2012 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse.
|
21996278 |
2012 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse.
|
21996278 |
2012 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, BDNF val(66)met has a significant impact on hippocampal volume independently of childhood abuse and psychiatric status.
|
22832736 |
2012 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the influence of childhood abuse and neglect on positive and negative psychotic-like experiences in adulthood and the potential moderating effect of the BDNF-Val66Met polymorphism.
|
21719879 |
2011 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met.
|
20703451 |
2011 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met.
|
20703451 |
2011 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the influence of childhood abuse and neglect on positive and negative psychotic-like experiences in adulthood and the potential moderating effect of the BDNF-Val66Met polymorphism.
|
21719879 |
2011 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study we analysed modulating effects of BDNF Val(66)Met polymorphism on the effects of physical maltreatment, rape and childhood sexual abuse on impulsive aggression.
|
19817874 |
2010 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study we analysed modulating effects of BDNF Val(66)Met polymorphism on the effects of physical maltreatment, rape and childhood sexual abuse on impulsive aggression.
|
19817874 |
2010 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This result suggests that Val66Met modulates the effect of childhood sexual abuse on the violence of SB.
|
17883407 |
2008 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This result suggests that Val66Met modulates the effect of childhood sexual abuse on the violence of SB.
|
17883407 |
2008 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study, we analyzed association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (C270T named formerly) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with methamphetamine (MAP) abuse in Japan.
|
15459944 |
2005 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study, we analyzed association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (C270T named formerly) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with methamphetamine (MAP) abuse in Japan.
|
15459944 |
2005 |
rs9470080
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A main effect of rs9470080 (p = 0.01) and gene x environment (physical abuse) interaction (p = 0.01) was found.
|
30711865 |
2019 |
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Logistic regressions with interaction terms (adjusted for sex and age) revealed that rs4680 interacted with total childhood adversity, emotional abuse and physical abuse in predicting panic disorder: Respective childhood adversities predicted panic disorder in carriers of the Val/Met or Met/Met genotype, but not Val/Val genotype.
|
29574383 |
2018 |
rs9470080
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Further, SNP rs9470080 in the main sample, and all four SNPs in the replication sample interacted with childhood abuse to predict PTSD severity (p values ranged from 0.002 to 0.006).
|
27078785 |
2016 |
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The functional polymorphism of the catecholamine-O-methyl-transferase (COMT) gene Val158Met significantly modulated the association between sexual abuse and anger-trait level (P = 0.001).
|
20002200 |
2010 |