|
rs1267969615
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The angiotensinogen M235T polymorphism might contribute to the multifactorial pathogenesis of gestational hypertension and pre-eclampsia.
|
17563539 |
2007 |
|
rs10889677
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the presence of IL-23R rs11209026, rs10889677 polymorphism might be markers for the genetic susceptibility to pre-eclampsia.
|
31123953 |
2019 |
|
rs11209026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the presence of IL-23R rs11209026, rs10889677 polymorphism might be markers for the genetic susceptibility to pre-eclampsia.
|
31123953 |
2019 |
|
rs1800469
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The TGF-β1 rs1800469 TT genotype was found more frequently in PE patients than in HP controls [CC vs. CT+TT: odds ratio (OR) = 1.71; 95% confidence interval (CI): 1.04-2.81; p = 0.033], indicating that the T allele of rs1800469 confers a risk for PE [OR = 1.46; 95% CI: 1.12-1.92; p = 0.006].
|
30875252 |
2019 |
|
rs2198532
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Rs1526172 and rs1245231 in the promoter region of COX-2 are correlated with the incidence of eclampsia, while rs2198532 has no correlation with eclampsia.
|
31378878 |
2019 |
|
rs2234693
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis was performed in order to determine the associations between the estrogen receptor α (ESR1) gene PvuII site (-397T/C, rs2234693) and XbaI site (-351A/G, rs9340799) polymorphisms with severe and mild pre-eclampsia.
|
30630878 |
2019 |
|
rs9340799
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis was performed in order to determine the associations between the estrogen receptor α (ESR1) gene PvuII site (-397T/C, rs2234693) and XbaI site (-351A/G, rs9340799) polymorphisms with severe and mild pre-eclampsia.
|
30630878 |
2019 |
|
rs2059806
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, it was found that the INSR rs2059806 SNP is also associated with pre-eclampsia phenotypes in two independent cohorts suggesting that genetic susceptibility may be implicated in the link between pre-eclampsia and subsequent vascular and metabolic diseases.
|
28117222 |
2017 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ORs for the COMT G472A polymorphism and pre-eclampsia were indicative of positive association under several genetic models.
|
28625321 |
2017 |
|
rs7020782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we aimed to investigate the relation between gene polymorphism of one of the products of trophoblasts, pregnancy-associated plasma protein A (PAPP-A) and PE/IUGR.A total of 147 women (IUGR, n = 61; PE, n = 47; IUGR + PE, n = 37; eclampsia, n = 2) were compared with 103 controls with respect to the sequencing of exon 14 of the PAPP-A gene to detect (rs7020782) polymorphism.
|
26520690 |
2015 |
|
rs7576192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs7576192 genotype showed significant differences between controls and multiparous PE patients (χ(2)=4.6088, df=1, P=0.0319, OR=0.6379, 95% CI 0.4223-0.9634).
|
26313529 |
2015 |
|
rs7579169
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs7579169 CC genotype was found to have a significantly higher frequency in PE patients than in controls [TT vs TC+CC: odds ratio (OR)=2.278, p=0.040], indicating that the C allele of rs7579169 confers a risk for PE [OR=1.4440, 95% confidence interval (CI) 1.0517-1.9827, p=0.0229].
|
26313529 |
2015 |
|
rs3756261
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study we found further evidence for the association of polymorphism in the EGF gene with pre-eclampsia and the weight of babies at birth and identified rs3756261A>G as the SNP that makes the most significant contribution to this association.
|
24754849 |
2014 |
|
rs397507444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the MTHFR 677T allele might be associated with increased pre-eclampsia risk in Asian and white ethnicity and the subgroup of severe pre-eclampsia, while no association is observed between the MTHFR A1298C polymorphism and pre-eclampsia.
|
24898880 |
2014 |
|
rs1222213359
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the meta-analysis revealed no association between pre-eclampsia and the VEGF -1154 A/G and 2578 A/C polymorphisms
|
23957473 |
2013 |
|
rs1799889
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between the SERPINE1 (PAI-1) 4G/5G insertion/deletion promoter polymorphism (rs1799889) and pre-eclampsia: a systematic review and meta-analysis.
|
23180602 |
2013 |
|
rs1800595
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of this study was to investigate the association of MTHFR 677C>T (rs1801133); 1298A>C (rs1801131) and F5 1691G>A (rs6025); 4070A>G (rs1800595) polymorphisms with pre-eclampsia and recurrent pregnancy loss among Sinhalese women in Sri Lanka.
|
22540831 |
2012 |
|
rs1801131
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of this study was to investigate the association of MTHFR 677C>T (rs1801133); 1298A>C (rs1801131) and F5 1691G>A (rs6025); 4070A>G (rs1800595) polymorphisms with pre-eclampsia and recurrent pregnancy loss among Sinhalese women in Sri Lanka.
|
22540831 |
2012 |
|
rs1801133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of this study was to investigate the association of MTHFR 677C>T (rs1801133); 1298A>C (rs1801131) and F5 1691G>A (rs6025); 4070A>G (rs1800595) polymorphisms with pre-eclampsia and recurrent pregnancy loss among Sinhalese women in Sri Lanka.
|
22540831 |
2012 |
|
rs2507800
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The prevalence of ANGPT1 rs2507800 TT genotype was reduced in women with pre-eclampsia [P = 0.01, adjusted odds ratio (aOR), 0.5; 95% confidence interval (CI), 0.3-0.9], hypertensive SGA (P = 0.04, aOR, 0.5; 95% CI, 0.2-0.9) and SGA with abnormal uterine artery Doppler (P = 0.009, aOR, 0.4.
|
22205728 |
2012 |
|
rs6025
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of this study was to investigate the association of MTHFR 677C>T (rs1801133); 1298A>C (rs1801131) and F5 1691G>A (rs6025); 4070A>G (rs1800595) polymorphisms with pre-eclampsia and recurrent pregnancy loss among Sinhalese women in Sri Lanka.
|
22540831 |
2012 |
|
rs351855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For Gly388Arg polymorphism of FGFR4 we found no significant association between controls and PE patients.
|
21827571 |
2011 |
|
rs770016471
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Maternal/newborn genotype contribution of the renin-angiotensin system (Met235Thr, Thr174Met, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A- AT2R2, 83A/G-REN) to the risk of pre-eclampsia: a Romanian study.
|
21436209 |
2011 |
|
rs2890565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results of this study suggest that UTS2 single gene (S89N) polymorphism is not associated with pre-eclampsia.
|
20653105 |
2010 |
|
rs2536512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest a role of SOD3 Ala40Thr single nucleotide polymorphism in the risk of severe fetal growth restriction-complicated pre-eclampsia.
|
19108943 |
2009 |