|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The polymorphisms of eNOS G894T and ET-2 A985G genes are correlated with the occurrence of eclampsia.
|
31486478 |
2019 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The aim of this study was to test the hypothesis that inflammatory cytokines impairs endothelium-dependent relaxation and NO production gets vitiated due to eNOs Glu298Asp gene polymorphism causing endothelial dysfunction in eclampsia.
|
22958187 |
2013 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Glu298Asp polymorphism in the eNOS gene could be an individual's risk factor and may modulate progression to an eclampsia complication of preeclampsia in the Turkish population.
|
21793998 |
2011 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We evaluated the association of the mutated genotypes Met235Thr-AGT, Thr174Met-AGT, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A-AT2R2, (83)A/G-REN with the risk and outcome of pre-eclampsia; we also investigated whether genes in newborns increase maternal risk of pre-eclampsia.
|
21436209 |
2011 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
As observed in this study Glu298Asp eNOS gene polymorphism did not showed significant association with pre-eclampsia.
|
20047583 |
2010 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The well-known M268T [M235T] polymorphism was not associated with pre-eclampsia.
|
18645251 |
2008 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In all, 17 studies (including 1446 cases and 3829 controls) published in English between 1993 and October 2006 on the association of angiotensinogen gene M235T polymorphism with preeclampsia/eclampsia were selected.
|
18698203 |
2008 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The angiotensinogen M235T polymorphism might contribute to the multifactorial pathogenesis of gestational hypertension and pre-eclampsia.
|
17563539 |
2007 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We investigated the role of eNOS T-786C, G894T and 4a4b polymorphisms in predisposing to both pre-eclampsia and the recurrence of negative pregnancy events, per se and in the presence of angiotensin-converting enzyme (ACE) DD genotype, and investigated their influence on maternal-fetal flow in 106 non-thrombophilic women with a history of pre-eclampsia, compared with 106 women with a history of normal pregnancy.
|
16915032 |
2006 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Among these are the angiotensinogen (AGT) gene variant Met235Threo, which has been associated with pre-eclampsia and the endothelial nitric oxide synthase (eNOS) polymorphism Glu298Asp, which has been associated with both pre-eclampsia and abruptio placentae, a condition that often co-exists with pre-eclampsia.
|
16059745 |
2005 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
No association was demonstrated between the M235T variant of the AGT gene and pre-eclampsia or abruptio placentae.
|
16059745 |
2005 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Our study shows that the M235T variant in the gene encoding angiotensinogen could be a risk factor in mild and severe pre-eclampsia.
|
12417054 |
2003 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The findings of this study suggest that polymorphisms of MTHFR C677T genes were not associated with pre-eclampsia in Hakka pregnant women from southern China, but additional studies are necessary to explore the mechanisms involving it.
|
31452430 |
2019 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Methylenetetrahydrofolate reductase C677T polymorphism and Factor V Leiden variant in Mexican women with preeclampsia/eclampsia.
|
15905108 |
2005 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population.
|
15387863 |
2004 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We genotyped a total of 171 cases with preeclampsia or eclampsia and 185 normotensive control subjects for the methylenetetrahydrofolate reductase (MTHFR) 677 C --> T genotype.
|
10655155 |
2000 |
|
rs11549465
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We determined whether maternal blood c.1722C>T (Pro582Ser) and c.1790G>A (Ala588Thr) polymorphisms in exon 12 of the HIF-1α gene are associated with pre-eclampsia.
|
21979130 |
2012 |
|
rs11549467
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We determined whether maternal blood c.1722C>T (Pro582Ser) and c.1790G>A (Ala588Thr) polymorphisms in exon 12 of the HIF-1α gene are associated with pre-eclampsia.
|
21979130 |
2012 |
|
rs4762
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Angiotensinogen gene M235T and T174M polymorphisms and susceptibility of pre-eclampsia: a meta-analysis.
|
22881375 |
2012 |
|
rs1267969615
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We evaluated the association of the mutated genotypes Met235Thr-AGT, Thr174Met-AGT, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A-AT2R2, (83)A/G-REN with the risk and outcome of pre-eclampsia; we also investigated whether genes in newborns increase maternal risk of pre-eclampsia.
|
21436209 |
2011 |
|
rs1341667
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The 10q22 chromosomal region with genomic linkage to pre-eclampsia in Dutch females shows a parent-of-origin effect with maternal transmission of the Y153H susceptibility allele of the STOX1 gene.
|
20716964 |
2011 |
|
rs4762
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We evaluated the association of the mutated genotypes Met235Thr-AGT, Thr174Met-AGT, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A-AT2R2, (83)A/G-REN with the risk and outcome of pre-eclampsia; we also investigated whether genes in newborns increase maternal risk of pre-eclampsia.
|
21436209 |
2011 |
|
rs1341667
|
|
|
0.020 |
GeneticVariation |
BEFREE |
By using complementary in vitro and ex vivo approaches, we show that the risk allele (Y153H) of the pre-eclampsia susceptibility gene STOX1 negatively regulates trophoblast invasion by upregulation of the cell-cell adhesion protein alpha-T-catenin (CTNNA3).
|
20400461 |
2010 |
|
rs11549465
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here we studied whether two single nucleotide sequence variants, c.1744 C>T that changes residue 582 of HIF-1alpha from proline to serine (P582S) and c.1762 G>A that changes residue 588 of HIF-1alpha from alanine to threonine (A588T) in the exon 12 of the HIF1A gene, are associated with pre-eclampsia.
|
18980686 |
2008 |
|
rs11549467
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here we studied whether two single nucleotide sequence variants, c.1744 C>T that changes residue 582 of HIF-1alpha from proline to serine (P582S) and c.1762 G>A that changes residue 588 of HIF-1alpha from alanine to threonine (A588T) in the exon 12 of the HIF1A gene, are associated with pre-eclampsia.
|
18980686 |
2008 |