rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
PTPN22 1858C>T gene polymorphism in patients with SLE: association with serological and clinical results.
|
24985973 |
2014 |
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete.
|
21543514 |
2011 |
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
|
15273934 |
2004 |
rs10516487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
|
21078628 |
2011 |
rs10516487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
rs10489265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate the association, two single-nucleotide polymorphisms (SNPs: rs2205960 and rs10489265) were genotyped in 814 SLE patients.
|
23936824 |
2013 |
rs1051169
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratified analyses showed that the rs1051169 polymorphism was associated with an increased risk of neurologic disorder in SLE patients (C vs. G: OR=1.78, 95% CI, 1.22-2.59, p=0.003; GC vs. GG: OR=2.33, 95% CI, 1.14-4.77, P=0.019; CC vs. GG: OR=3.02, 95% CI, 1.39-6.53, p=0.004; CC+GC vs. GG: OR=2.57, 95% CI=1.31-5.04, p=0.005).
|
31271591 |
2020 |
rs1061622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lack of association between the Met196Arg polymorphism in the TNFR2 gene and autoimmune diseases accompanied by vasculitis including SLE in Japanese.
|
11169260 |
2001 |
rs12720270
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
rs12720356
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
rs13277113
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed more frequent heterozygous GA genotypic pattern (rs13277113) in our SLE patients compared to that in controls; and it was associated with disease flares.
|
27864698 |
2017 |
rs17266594
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
|
21078628 |
2011 |
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Glu298Asp eNOS polymorphism is not associated with SLE.
|
19318399 |
2009 |
rs2069705
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model.
|
19919944 |
2010 |
rs2069718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model.
|
19919944 |
2010 |
rs2243188
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor C allele of rs2243188, relative to the major A allele, appeared to have a significantly lower frequency in SLE patients (31.0%) as compared with controls (35.5%) (χ(2) = 5.19, p = 0.023).
|
24819332 |
2014 |
rs2304256
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
rs231775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CTLA4 +49 A/G (rs231775) polymorphism influences susceptibility to SLE in South Indian Tamils.
|
24758310 |
2014 |
rs2397084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival.
|
26515887 |
2016 |
rs2430561
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model.
|
19919944 |
2010 |
rs2736340
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
rs280500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
rs28362930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The allele frequency of G (rs28362930) was higher in S</span>LE patients with renal disorder.
|
31394943 |
2019 |
rs2910164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G and C allele frequencies of rs2</span>910164 were 39 and 61% in SLE patients, but 36 and 64% in healthy group (P = 0.990), respectively.
|
20845080 |
2011 |
rs3077
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, HLA-DP polymorphisms (rs3077 and rs9277535) were associated with SLE susceptibility and the levels of some inflammatory cytokines in SLE patients.
|
28094303 |
2017 |