|
rs2069705
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model.
|
19919944 |
2010 |
|
rs3181032
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model.
|
19919944 |
2010 |
|
rs2430561
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model.
|
19919944 |
2010 |
|
rs2069718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model.
|
19919944 |
2010 |
|
rs548234
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
|
rs2736340
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
|
rs10516487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
|
rs12720356
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs34536443
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs2304256
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs12720270
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs280500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Glu298Asp eNOS polymorphism is not associated with SLE.
|
19318399 |
2009 |
|
rs4581
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Val/Leu247 polymorphism of β2-glycoprotein I and thrombosis in Chinese patients with SLE.
|
24661363 |
2015 |
|
rs929763
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additional analysis showed that the genotype of the rs929763 and rs3805455 of the GABRP gene were also significantly associated with female SLE patients (P < 0.0001, P = 0.005, resp.).
|
26634217 |
2015 |
|
rs3805455
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additional analysis showed that the genotype of the rs929763 and rs3805455 of the GABRP gene were also significantly associated with female SLE patients (P < 0.0001, P = 0.005, resp.).
|
26634217 |
2015 |
|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete.
|
21543514 |
2011 |
|
rs7574865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, the stratified meta-analysis also demonstrate that the STAT4 rs7574865 polymorphism is associated with the presence of autoantibodies with systemic reactivity (anti-ds-DNA antibodies) in SLE patients (OR = 1.37; 95% CI = 1.21 - 1.56, P = 1.12 × 10(-6)).
|
23628400 |
2013 |
|
rs3824662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GATA3 rs3824662 is not associated with susceptibility to SLE either in adult or in pediatric patients; however, in pSLE patients, the heterozygous AC genotype could be considered a risk factor for LN.
|
30301440 |
2018 |
|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
|
15273934 |
2004 |
|
rs2397084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival.
|
26515887 |
2016 |
|
rs549908
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-18 105 A>C polymorphism contributes to renal manifestations in patients with SLE.
|
19387647 |
2009 |
|
rs3077
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, HLA-DP polymorphisms (rs3077 and rs9277535) were associated with SLE susceptibility and the levels of some inflammatory cytokines in SLE patients.
|
28094303 |
2017 |
|
rs9277535
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, HLA-DP polymorphisms (rs3077 and rs9277535) were associated with SLE susceptibility and the levels of some inflammatory cytokines in SLE patients.
|
28094303 |
2017 |
|
rs1061622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lack of association between the Met196Arg polymorphism in the TNFR2 gene and autoimmune diseases accompanied by vasculitis including SLE in Japanese.
|
11169260 |
2001 |