Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2736340
rs2736340
0.010 GeneticVariation BEFREE SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642). 26420661

2016

dbSNP: rs4581
rs4581
0.010 GeneticVariation BEFREE Val/Leu247 polymorphism of β2-glycoprotein I and thrombosis in Chinese patients with SLE. 24661363

2015

dbSNP: rs548234
rs548234
0.010 GeneticVariation BEFREE SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642). 26420661

2016

dbSNP: rs10516487
rs10516487
0.020 GeneticVariation BEFREE This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population. 21078628

2011

dbSNP: rs10516487
rs10516487
0.020 GeneticVariation BEFREE SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642). 26420661

2016

dbSNP: rs17266594
rs17266594
0.010 GeneticVariation BEFREE This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population. 21078628

2011

dbSNP: rs13277113
rs13277113
BLK
0.010 GeneticVariation BEFREE We observed more frequent heterozygous GA genotypic pattern (rs13277113) in our SLE patients compared to that in controls; and it was associated with disease flares. 27864698

2017

dbSNP: rs231775
rs231775
0.010 GeneticVariation BEFREE The CTLA4 +49 A/G (rs231775) polymorphism influences susceptibility to SLE in South Indian Tamils. 24758310

2014

dbSNP: rs3805455
rs3805455
0.010 GeneticVariation BEFREE Additional analysis showed that the genotype of the rs929763 and rs3805455 of the GABRP gene were also significantly associated with female SLE patients (P < 0.0001, P = 0.005, resp.). 26634217

2015

dbSNP: rs929763
rs929763
0.010 GeneticVariation BEFREE Additional analysis showed that the genotype of the rs929763 and rs3805455 of the GABRP gene were also significantly associated with female SLE patients (P < 0.0001, P = 0.005, resp.). 26634217

2015

dbSNP: rs3824662
rs3824662
0.010 GeneticVariation BEFREE GATA3 rs3824662 is not associated with susceptibility to SLE either in adult or in pediatric patients; however, in pSLE patients, the heterozygous AC genotype could be considered a risk factor for LN. 30301440

2018

dbSNP: rs3077
rs3077
0.010 GeneticVariation BEFREE In conclusion, HLA-DP polymorphisms (rs3077 and rs9277535) were associated with SLE susceptibility and the levels of some inflammatory cytokines in SLE patients. 28094303

2017

dbSNP: rs9277535
rs9277535
0.010 GeneticVariation BEFREE In conclusion, HLA-DP polymorphisms (rs3077 and rs9277535) were associated with SLE susceptibility and the levels of some inflammatory cytokines in SLE patients. 28094303

2017

dbSNP: rs3181032
rs3181032
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs2069705
rs2069705
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs2069718
rs2069718
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs2430561
rs2430561
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs2397084
rs2397084
0.010 GeneticVariation BEFREE IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival. 26515887

2016

dbSNP: rs549908
rs549908
0.010 GeneticVariation BEFREE IL-18 105 A>C polymorphism contributes to renal manifestations in patients with SLE. 19387647

2009

dbSNP: rs2243188
rs2243188
0.010 GeneticVariation BEFREE The minor C allele of rs2243188, relative to the major A allele, appeared to have a significantly lower frequency in SLE patients (31.0%) as compared with controls (35.5%) (χ(2) = 5.19, p = 0.023). 24819332

2014

dbSNP: rs2910164
rs2910164
0.010 GeneticVariation BEFREE The G and C allele frequencies of rs2</span>910164 were 39 and 61% in SLE patients, but 36 and 64% in healthy group (P = 0.990), respectively. 20845080

2011

dbSNP: rs3746444
rs3746444
0.010 GeneticVariation BEFREE The C and T allele frequencies of rs3746444 were 15 and 85% in SLE patients, but 14 and 86% in healthy group (P = 0.702), respectively. 20845080

2011

dbSNP: rs1799983
rs1799983
0.010 GeneticVariation BEFREE Glu298Asp eNOS polymorphism is not associated with SLE. 19318399

2009

dbSNP: rs2476601
rs2476601
0.030 GeneticVariation BEFREE PTPN22 1858C>T gene polymorphism in patients with SLE: association with serological and clinical results. 24985973

2014

dbSNP: rs2476601
rs2476601
0.030 GeneticVariation BEFREE Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete. 21543514

2011