Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10489265
rs10489265
0.010 GeneticVariation BEFREE To replicate the association, two single-nucleotide polymorphisms (SNPs: rs2205960 and rs10489265) were genotyped in 814 SLE patients. 23936824

2013

dbSNP: rs7574865
rs7574865
0.010 GeneticVariation BEFREE Furthermore, the stratified meta-analysis also demonstrate that the STAT4 rs7574865 polymorphism is associated with the presence of autoantibodies with systemic reactivity (anti-ds-DNA antibodies) in SLE patients (OR = 1.37; 95% CI = 1.21 - 1.56, P = 1.12 × 10(-6)). 23628400

2013

dbSNP: rs17266594
rs17266594
0.010 GeneticVariation BEFREE This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population. 21078628

2011

dbSNP: rs2910164
rs2910164
0.010 GeneticVariation BEFREE The G and C allele frequencies of rs2</span>910164 were 39 and 61% in SLE patients, but 36 and 64% in healthy group (P = 0.990), respectively. 20845080

2011

dbSNP: rs3746444
rs3746444
0.010 GeneticVariation BEFREE The C and T allele frequencies of rs3746444 were 15 and 85% in SLE patients, but 14 and 86% in healthy group (P = 0.702), respectively. 20845080

2011

dbSNP: rs2069705
rs2069705
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs2069718
rs2069718
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs2430561
rs2430561
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs3181032
rs3181032
0.010 GeneticVariation BEFREE SLE susceptibility association was significant with rs2069705 in the promoter (adjusted OR 2.27, p=0.0024) and marginal with rs3181032 in the promoter (p=0.037), rs2430561 in intron 1 (p=0.022) and rs2069718 in intron 3 (p=0.026) in a recessive genetic model. 19919944

2010

dbSNP: rs1799983
rs1799983
0.010 GeneticVariation BEFREE Glu298Asp eNOS polymorphism is not associated with SLE. 19318399

2009

dbSNP: rs549908
rs549908
0.010 GeneticVariation BEFREE IL-18 105 A>C polymorphism contributes to renal manifestations in patients with SLE. 19387647

2009

dbSNP: rs1061622
rs1061622
0.010 GeneticVariation BEFREE Lack of association between the Met196Arg polymorphism in the TNFR2 gene and autoimmune diseases accompanied by vasculitis including SLE in Japanese. 11169260

2001