|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
PTPN22 1858C>T gene polymorphism in patients with SLE: association with serological and clinical results.
|
24985973 |
2014 |
|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete.
|
21543514 |
2011 |
|
rs2476601
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
|
15273934 |
2004 |
|
rs10516487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
|
rs10516487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
|
21078628 |
2011 |
|
rs1051169
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratified analyses showed that the rs1051169 polymorphism was associated with an increased risk of neurologic disorder in SLE patients (C vs. G: OR=1.78, 95% CI, 1.22-2.59, p=0.003; GC vs. GG: OR=2.33, 95% CI, 1.14-4.77, P=0.019; CC vs. GG: OR=3.02, 95% CI, 1.39-6.53, p=0.004; CC+GC vs. GG: OR=2.57, 95% CI=1.31-5.04, p=0.005).
|
31271591 |
2020 |
|
rs12720270
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs12720356
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs2304256
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs280500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs28362930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The allele frequency of G (rs28362930) was higher in S</span>LE patients with renal disorder.
|
31394943 |
2019 |
|
rs34536443
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE protection was associated with TYK2 risk infection variants affecting residually its catalytic domain, rs12720356 (OR = 0.308; p = 0.041) and rs34536443 (OR = 0.370; p = 0.034), but not with rs2304256, rs12720270, and rs280500.
|
31434951 |
2019 |
|
rs741761
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were differences in the genotype frequencies and allele frequencies of rs741761 between SLE patients with and without arthritis.
|
31394943 |
2019 |
|
rs3824662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GATA3 rs3824662 is not associated with susceptibility to SLE either in adult or in pediatric patients; however, in pSLE patients, the heterozygous AC genotype could be considered a risk factor for LN.
|
30301440 |
2018 |
|
rs13277113
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed more frequent heterozygous GA genotypic pattern (rs13277113) in our SLE patients compared to that in controls; and it was associated with disease flares.
|
27864698 |
2017 |
|
rs3077
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, HLA-DP polymorphisms (rs3077 and rs9277535) were associated with SLE susceptibility and the levels of some inflammatory cytokines in SLE patients.
|
28094303 |
2017 |
|
rs9277535
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, HLA-DP polymorphisms (rs3077 and rs9277535) were associated with SLE susceptibility and the levels of some inflammatory cytokines in SLE patients.
|
28094303 |
2017 |
|
rs2397084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival.
|
26515887 |
2016 |
|
rs2736340
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
|
rs548234
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
|
26420661 |
2016 |
|
rs3805455
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additional analysis showed that the genotype of the rs929763 and rs3805455 of the GABRP gene were also significantly associated with female SLE patients (P < 0.0001, P = 0.005, resp.).
|
26634217 |
2015 |
|
rs4581
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Val/Leu247 polymorphism of β2-glycoprotein I and thrombosis in Chinese patients with SLE.
|
24661363 |
2015 |
|
rs929763
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additional analysis showed that the genotype of the rs929763 and rs3805455 of the GABRP gene were also significantly associated with female SLE patients (P < 0.0001, P = 0.005, resp.).
|
26634217 |
2015 |
|
rs2243188
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor C allele of rs2243188, relative to the major A allele, appeared to have a significantly lower frequency in SLE patients (31.0%) as compared with controls (35.5%) (χ(2) = 5.19, p = 0.023).
|
24819332 |
2014 |
|
rs231775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CTLA4 +49 A/G (rs231775) polymorphism influences susceptibility to SLE in South Indian Tamils.
|
24758310 |
2014 |