|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the present study, an association of rs7521902 (WNT4) and rs10859871 (VEZT) was confirmed in women with endometriosis at the genotypic but not the allelic level.
|
28901453 |
2017 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the present study, an association of rs7521902 (WNT4) and rs10859871 (VEZT) was confirmed in women with endometriosis at the genotypic but not the allelic level.
|
28901453 |
2017 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Endometriosis risk SNPs (including rs10859871) located within this locus demonstrated evidence for ITALIC! cis-eQTLs on ITALIC!VEZT expression.
|
27005890 |
2016 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Genome-wide and candidate-gene association studies for endometriosis have identified 10 independent risk loci, and of these, nine (rs7521902, rs13394619, rs4141819, rs6542095, rs1519761, rs7739264, rs12700667, rs1537377, and rs10859871) are polymorphic in European populations.
|
26337243 |
2015 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Meta-analysis with previous data confirmed the rs10859871 </span>SNP as that with the strongest evidence for association with endometriosis (OR = 1.19, 95% CI: 1.15-1.24, P = 7.9 × 10(-20)).
|
25678572 |
2015 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Genome-wide and candidate-gene association studies for endometriosis have identified 10 independent risk loci, and of these, nine (rs7521902, rs13394619, rs4141819, rs6542095, rs1519761, rs7739264, rs12700667, rs1537377, and rs10859871) are polymorphic in European populations.
|
26337243 |
2015 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
No significant association was found between endometriosis and rs7521902 (A/C), rs16826658 (G/T), or rs7515106 (C/T).
|
25682310 |
2015 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
TaqMan allelic discrimination technique was used to investigate the relationship between endometriosis and four single-nucleotide polymorphisms (rs16826658, rs3820282, rs2235529, and rs7521902) in WNT4 gene.
|
26139156 |
2015 |
|
rs7521902
|
|
A |
0.850 |
GeneticVariation |
GWASCAT |
Genome-wide association study link novel loci to endometriosis.
|
23472165 |
2013 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
The meta-analysis showed that rs7521902 was associated with endometriosis at a genome-wide significance (p(meta)=2.23×10(-9)) while for rs1250248, a genome-wide significant p(meta) value of 3.89×10(-9) was detected only in association with severe forms.
|
23142796 |
2013 |
|
rs10859871
|
|
C |
0.850 |
GeneticVariation |
GWASDB |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs10859871
|
|
C |
0.850 |
GeneticVariation |
GWASCAT |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs7521902
|
|
A |
0.850 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analysis identifies new endometriosis risk loci.
|
23104006 |
2012 |
|
rs7521902
|
|
A |
0.850 |
GeneticVariation |
GWASDB |
Genome-wide association meta-analysis identifies new endometriosis risk loci.
|
23104006 |
2012 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Fine mapping results identified a number of SNPs showing stronger association (0.004 < P < 0.032) with endometriosis risk than the original GWAS SNP (rs13394619) (P = 0.034).
|
25788566 |
2015 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Notably, three coding variants in GREB1 (near rs13394619) and CDKN2B-AS1 (near rs1537377) also showed nominally significant associations with endometriosis.
|
26337243 |
2015 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Is it possible to replicate the genetic association of single nucleotide polymorphisms (SNPs) rs13394619, rs4141819, rs7739264, rs17694933 and rs10859871 in five genetic loci previously identified as associated with endometriosis in an Italian Caucasian population?
|
25678572 |
2015 |
|
rs13394619
|
|
G |
0.840 |
GeneticVariation |
GWASCAT |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs13394619
|
|
G |
0.840 |
GeneticVariation |
GWASDB |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs2235529
|
|
|
0.820 |
GeneticVariation |
BEFREE |
This might constitute the first step towards identifying polymorphism combinations that predispose to endometriosis (IFNG (CA) repeat, GSTM1 null genotype, GSTP1 rs1695, WNT4 rs16826658 and WNT4 rs2235529) in a large cohort of patients with well-defined inclusion criteria.
|
31821471 |
2020 |
|
rs12700667
|
|
A |
0.820 |
GeneticVariation |
GWASCAT |
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.
|
28537267 |
2017 |
|
rs12700667
|
|
|
0.820 |
GeneticVariation |
BEFREE |
The study suggests that the endometriosis-associated genetic polymorphisms (rs12700667) from GWAS be associated with the risk of developing ovarian endometriosis in North Chinese women.
|
27233752 |
2017 |
|
rs12700667
|
|
|
0.820 |
GeneticVariation |
GWASCAT |
Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis.
|
28333195 |
2017 |