|
rs1398830127
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The present meta-analysis suggests that GABBR1 G1465A polymorphism is associated with the risk of TLE.
|
21621395 |
2011 |
|
rs1805057
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The present meta-analysis suggests that GABBR1 G1465A polymorphism is associated with the risk of TLE.
|
21621395 |
2011 |
|
rs1398830127
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We also analysed in our study population the GABA(B) receptor 1 c.1465G>A and the prodynorphin promoter 68-bp repeat polymorphisms, previously associated with temporal lobe epilepsy.
|
18355961 |
2008 |
|
rs1398830127
|
|
|
0.070 |
GeneticVariation |
BEFREE |
However, six replication studies did not show significant association between the G1465A GABABR1 gene variant and TLE.
|
18255321 |
2008 |
|
rs1805057
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We also analysed in our study population the GABA(B) receptor 1 c.1465G>A and the prodynorphin promoter 68-bp repeat polymorphisms, previously associated with temporal lobe epilepsy.
|
18355961 |
2008 |
|
rs1805057
|
|
|
0.070 |
GeneticVariation |
BEFREE |
However, six replication studies did not show significant association between the G1465A GABABR1 gene variant and TLE.
|
18255321 |
2008 |
|
rs1398830127
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Recently a coding nonsynonymous single-nucleotide polymorphism (SNP; G1465A) in the GABBR1 gene was reported to be associated with the incidence and severity of temporal lobe epilepsy (TLE).
|
16499773 |
2006 |
|
rs1805057
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Recently a coding nonsynonymous single-nucleotide polymorphism (SNP; G1465A) in the GABBR1 gene was reported to be associated with the incidence and severity of temporal lobe epilepsy (TLE).
|
16499773 |
2006 |
|
rs1398830127
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our results indicate that TLE preceded by FS is not associated with the polymorphisms or mutations in the GABBR1 gene, including the G1465A polymorphism.
|
15799783 |
2005 |
|
rs1398830127
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Recently, it is reported that the GABA(B)R1 polymorphism (G1465A) conferred a highly increased susceptibility to TLE.
|
16278087 |
2005 |
|
rs1805057
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our results indicate that TLE preceded by FS is not associated with the polymorphisms or mutations in the GABBR1 gene, including the G1465A polymorphism.
|
15799783 |
2005 |
|
rs1805057
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Recently, it is reported that the GABA(B)R1 polymorphism (G1465A) conferred a highly increased susceptibility to TLE.
|
16278087 |
2005 |
|
rs1398830127
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The results of this study indicate that the GABA(B[1]) polymorphism (G1465A) confers a highly increased susceptibility to TLE.
|
12601092 |
2003 |
|
rs1805057
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The results of this study indicate that the GABA(B[1]) polymorphism (G1465A) confers a highly increased susceptibility to TLE.
|
12601092 |
2003 |
|
rs6265
|
|
|
0.040 |
GeneticVariation |
BEFREE |
BDNF Val66Met polymorphism is not related with temporal lobe epilepsy caused by hippocampal sclerosis in Brazilian population.
|
30015148 |
2018 |
|
rs759834365
|
|
|
0.040 |
GeneticVariation |
BEFREE |
BDNF Val66Met polymorphism is not related with temporal lobe epilepsy caused by hippocampal sclerosis in Brazilian population.
|
30015148 |
2018 |
|
rs6265
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our findings suggested that BDNF Val66Met polymorphism might be correlated with epileptogenesis, and Met66 allele might play a protective role against the occurrence of TLE.
|
26000807 |
2016 |
|
rs759834365
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our findings suggested that BDNF Val66Met polymorphism might be correlated with epileptogenesis, and Met66 allele might play a protective role against the occurrence of TLE.
|
26000807 |
2016 |
|
rs6265
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In spite of abundant evidence that Val66Met BDNF polymorphism has an impact on several different neurological or psychiatric disorders, we conclude that a major clinical impact of Val66Met polymorphism as a disease modifier in temporal lobe epilepsy is probably unlikely.
|
19896331 |
2010 |
|
rs759834365
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In spite of abundant evidence that Val66Met BDNF polymorphism has an impact on several different neurological or psychiatric disorders, we conclude that a major clinical impact of Val66Met polymorphism as a disease modifier in temporal lobe epilepsy is probably unlikely.
|
19896331 |
2010 |
|
rs6265
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In this study we attempted to replicate the initial finding in a patient-control population of European ancestry and in addition tested whether the functional Val66Met polymorphism is associated with temporal lobe epilepsy (TLE).
|
16105728 |
2006 |
|
rs759834365
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In this study we attempted to replicate the initial finding in a patient-control population of European ancestry and in addition tested whether the functional Val66Met polymorphism is associated with temporal lobe epilepsy (TLE).
|
16105728 |
2006 |
|
rs10868235
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Depressive disorders accounted for this results and independent variables associated with depressive disorders in TLE were female sex (OR=2.59; 95%CI=1.15-5.82; p=0.021), presence of concomitant anxiety disorders (OR=3.72; 95%CI=1.71-8.06; p=0.001) or psychotic disorders (OR=3.86; 95%CI=1.12-13.25; p=0.032), A/A genotype in the rs1867283 NTRK2 gene (OR=3.06; 95%CI=1.25-7.50; p=0.015) and C/C genotype in the rs10868235 NTRK2 gene (OR=3.54; 1.55-8.08; p=0.003).
|
28550723 |
2017 |
|
rs10868235
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Patients with TLE showed a statistical trend for increase of the T/T genotype in rs10868235 compared to control (O.R.=1.90; 95%CI=1.17-3.09; p=0.01).
|
28863320 |
2017 |
|
rs1799990
|
|
|
0.020 |
GeneticVariation |
BEFREE |
M129V polymorphism in the prion protein gene is not associated with mesial temporal lobe epilepsy in a Han Chinese population.
|
18549399 |
2008 |