|
rs3738894
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The gene-Environment interaction between rs3738894 and smoking history was associated with the risk of esophageal cancer.
|
31269493 |
2020 |
|
rs1048943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In additional, five variants on five genes were rated as strong cumulative epidemiological evidence for a nominally significant association with EC and ESCC risk, including CYP1A1 rs1048943, EGF rs444903, HOTAIR rs920778, MMP2 rs243865, and PLCE1 rs2274223, 10 variants were rated as moderate, and 18 variants were rated as weak.
|
30793520 |
2019 |
|
rs10509670
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results showed that the minor alleles of rs3765524, rs2274223, and rs10509670 were associated with increased risk of EC and GC.
|
30931333 |
2019 |
|
rs115510139
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratified analysis was performed by gender, age, alcohol drinking, BMI, TNM stage and lymph node metastasis, the results showed that rs7436, rs115510139 and rs6720283 were significantly associated with the risk of EC in different groups (all p < 0.05).
|
31425922 |
2019 |
|
rs11674595
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results reveal the significant association between SNPs (rs11674595 and rs2072472) in the IL1R2 and EC risk in the Chinese Han population.
|
31744444 |
2019 |
|
rs2031920
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>CYP1A1</i> rs4646903 and <i>CYP2E1</i> rs2031920 polymorphisms were risk factors of GCC or EC, and the <i>GSTM1</i> null genotype may serve a protective role against EC.
|
31423187 |
2019 |
|
rs2072472
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results reveal the significant association between SNPs (rs11674595 and rs2072472) in the IL1R2 and EC risk in the Chinese Han population.
|
31744444 |
2019 |
|
rs2094258
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No correlation between rs873601 and rs2094258 and susceptibility to esophageal cancer</span> was found.
|
28952217 |
2019 |
|
rs2296147
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results of this case-control study showed that the polymorphic locus on ERCC5, rs2296147, could reduce the risk of esophageal cancer, which will help further understand the pathogenesis of esophageal cancer.
|
28952217 |
2019 |
|
rs315919
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study provided the first evidence that IL1RN rs3181052, rs452204, and rs315919 are correlated with a decreased risk of esophageal cancer in a Northwest Han Chinese population.
|
30995661 |
2019 |
|
rs3181052
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In stratified analyses </span>by age >55 years, rs3181052 reduced the risk of esophageal cancer in the dominant and overdominant models.
|
30995661 |
2019 |
|
rs452204
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study provided the first evidence that IL1RN rs3181052, rs452204, and rs315919 are correlated with a decreased risk of esophageal cancer in a Northwest Han Chinese population.
|
30995661 |
2019 |
|
rs6720283
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratified analysis was performed by gender, age, alcohol drinking, BMI, TNM stage and lymph node metastasis, the results showed that rs7436, rs115510139 and rs6720283 were significantly associated with the risk of EC in different groups (all p < 0.05).
|
31425922 |
2019 |
|
rs7436
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratified analysis was performed by gender, age, alcohol drinking, BMI, TNM stage and lymph node metastasis, the results showed that rs7436, rs115510139 and rs6720283 were significantly associated with the risk of EC in different groups (all p < 0.05).
|
31425922 |
2019 |
|
rs873601
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No correlation between rs873601 and rs2094258 and susceptibility to e</span>sophageal cancer was found.
|
28952217 |
2019 |
|
rs4767364
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aims to investigate the relationship between ALDH2 rs671 and c12orf30 rs4767364 polymorphisms in the chromosome 12q24 gene, and risk and prognosis of individuals developing esophageal cancer (ESCC) in Xinjiang Kazak and Han populations.
|
28464297 |
2018 |
|
rs10069690
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the four SNPs examined, rs10069690 and rs2242652 were correlated with esophageal cancer risk.
|
28060765 |
2017 |
|
rs11548103
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>S100A14</i> rs11548103 G>A polymorphism is associated with a decreased risk of esophageal cancer in a Chinese population.
|
29156846 |
2017 |
|
rs174538
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Flap endonuclease-1 rs174538 G>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population.
|
28319330 |
2017 |
|
rs2242652
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the four SNPs examined, rs10069690 and rs2242652 were correlated with esophageal cancer risk.
|
28060765 |
2017 |
|
rs2244438
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four of the 20 SNPs identified as high-risk SNPs in Chinese esophageal cancer showed increased risk for Chinese lung cancer, which included rs3769823 (OR = 1.26; 95% CI = 1.107-1.509; P = 0.02), rs10931936 (OR = 1.283; 95% CI = 1.100-1.495; P = 0.04), rs2244438 (OR = 1.294; 95% CI = 1.098-1.525; P = 0.04) and rs13016963 (OR = 1.268; 95% CI = 1.089-1.447; P = 0.04).
|
28542283 |
2017 |
|
rs2320615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results provide the first evidence that the rs2320615 in NAF1 was associated with reduced risk of esophageal cancer.
|
28454086 |
2017 |
|
rs3747093
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, we observed consistent associations between rs3747093 and multiple cancers (gastric cancer: OR = 0.85, P = 2.21 × 10<sup>-4</sup>; esophageal cancer: OR = 0.91, P = 2.57 × 10<sup>-2</sup>; colorectal cancer: OR = 0.80, P = 1.85 × 10<sup>-6</sup>; and breast cancer: OR = 0.87, P = 1.55 × 10<sup>-3</sup>).
|
28653172 |
2017 |
|
rs3856806
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a subgroup analysis by cancer type, <i>PPARG c.1347C>T</i> polymorphism was associated with risk of esophageal cancer and glioblastoma.
|
29254243 |
2017 |
|
rs895819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, no association was found between rs895819 and risk of gastric cancer or esophageal cancer.
|
29088869 |
2017 |