The association between the EPHX1 Tyr113His</span> and His139Arg polymorphisms and EC risk was pooled by odds ratios (ORs) together with their 95% confidence intervals (95%CIs).
Meta-analysis showed that the Tyr113His polymorphism was a stronger power trend towards risk for esophageal cancer using a recessive model (CC versus CT+TT, OR = 1.204, 95%CI = 1.001-1.450, P = 0.049).
No significant association was found in either the allele or genotype models for Tyr1</span>13His or His139Arg polymorphism with risk for esophageal cancer</span>.