The association between the EPHX1 Tyr113His and His139Arg</span> polymorphisms and EC risk was pooled by odds ratios (ORs) together with their 95% confidence intervals (95%CIs).
Meta-analysis of these seven studies for EPHX1 H</span>is139Arg polymorphism showed that EPHX1 His139Arg polymorphism was also not associated with esophageal cancer</span> risk under all genetic models.
No significant association was found in either the allele or genotype models for Tyr113His or His1</span>39Arg polymorphism with risk for esophageal cancer</span>.