Gene: TNFRSF1A ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800692
rs1800692
TNFRSF1A
0.010 GeneticVariation BEFREE In patients with TRAPS, rs1800692 T/T homozygotes were excessively rare (p<10(-4)) and TRAPS-like patients with this genotype experienced less fever. 23505244

2014
dbSNP: rs104895271
rs104895271
TNFRSF1A
0.010 GeneticVariation BEFREE The D12E substitution has been described only once to date, in a 4-year-old boy with fever. 23322460

2013
dbSNP: rs1424748509
rs1424748509
TNFRSF1A
0.010 GeneticVariation BEFREE Reported TNFRSF1A gene mutations in these nine index patients were C70S, T61I, C70G, C30Y, C30R, N101K, and N25D.Fever (100 %) was seen in all 23 cases. 22918594

2013
dbSNP: rs4149584
rs4149584
TNFRSF1A
0.010 GeneticVariation BEFREE Patients with R92Q mutations and patients with PFAPA displayed a higher rate of self-resolution or amelioration of the fever episodes than did TRAPS patients with structural mutations. 21225694

2011