Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Genome-wide association data have identified common genetic variants at 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A-CDKN2B), 11q23.3 (rs498872, PHLDB1), and 20q13.33 (rs6010620, RTEL1) as determinants of glioma risk. 20462933

2010

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Case-control analyses stratified into 4 molecular classes (defined by 1p-19q status, IDH mutation, and EGFR amplification) showed an association of rs4295627 and rs498872 with IDH-mutated gliomas (P < 10(-3)) and rs2736100 and rs6010620 with IDH wild-type gliomas (P < 10(-3) and P = .03). 23161787

2013

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Specific single nucleotides polymorphisms (SNPs) rs4977756 (CDKN2A/B), rs6010620 (RTEL1), rs498872 (PHLDB1), rs2736100 (TERT), and rs4295627 (CCDC26) have been associated with glioma susceptibility and are potential risk biomarkers. 31721021

2020

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE In analyses including glioma cases with a family history of brain tumours (n = 104) and control subjects free of glioma at baseline, three of seven SNPs were associated with glioma risk: rs2736100 (5p15.33, TERT), rs4977756 (9p21.3, CDKN2A-CDKN2B) and rs6010620 (20q13.33, RTEL1). 23115063

2013

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Seven independent chromosomal loci have robustly been associated with glioma risk: 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A-CDKN2B), 20q13.33 (rs6010620, RTEL1), and 11q23.3 (rs498872, PHLDB1), and two loci at 7p11.2 (rs11979158 and rs2252586, EGFR). 21825990

2011

dbSNP: rs2736100
rs2736100
G 0.900 GeneticVariation GWASDB We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Our group identified 5 risk loci for glioma susceptibility (TERT rs2736100, CCDC26 rs4295627, CDKN2A/CDKN2B rs4977756, RTEL1 rs6010620, and PHLDB1 rs498872). 20212223

2010

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation GWASDB Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk. 21827660

2011

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation GWASCAT Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation GWASCAT Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk. 21827660

2011

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Genome-wide association studies have recently identified single-nucleotide polymorphisms (SNP) in five loci at 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A/CDKN2B), 20q13.33 (rs6010620, RTEL1), and 11q23.3 (rs498872, PHLDB1) to be associated with glioma risk. 20847058

2010

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Four of the five SNPs previously reported by others were statistically significantly associated with increased risk of glioma in our study (rs2736100, rs4295627, rs4977756, and rs6010620); rs498872 was not associated with glioma in our study. 23903690

2013

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Taken together, these data suggested that TERT rs2736100 polymorphism may contribute to glioma susceptibility. 24888789

2014

dbSNP: rs2736100
rs2736100
C 0.900 GeneticVariation GWASCAT Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility. 30714141

2019

dbSNP: rs2736100
rs2736100
G 0.900 GeneticVariation GWASCAT Genome-wide association study of glioma and meta-analysis. 22886559

2012

dbSNP: rs2736100
rs2736100
G 0.900 GeneticVariation GWASDB Genome-wide association study of glioma and meta-analysis. 22886559

2012

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25). 26243184

2016

dbSNP: rs2736100
rs2736100
C 0.900 GeneticVariation GWASDB Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 24908248

2014

dbSNP: rs2736100
rs2736100
C 0.900 GeneticVariation GWASCAT Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 24908248

2014

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Overall, the authors identified 3 susceptibility loci for glioma risk at 20q13.33 (RTEL1 rs6010620 (P = 2.79 × 10(-6))), 11q23.3 (PHLDB1 rs498872 (P = 3.8 × 10(-6))), and 5p15.33 (TERT rs2736100 (P = 3.69 × 10(-4))) in this study population; these loci were also associated with glioblastoma risk (20q13.33: RTEL1 rs6010620 (P = 3.57 × 10(-7)); 11q23.3: PHLDB1 rs498872 (P = 7.24 × 10(-3)); 5p15.33: TERT rs2736100 and TERT rs2736098 (P = 1.21 × 10(-4) and P = 2.84 × 10(-4), respectively)). 21350045

2011

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE The role of telomerase reverse transcriptase (TERT) in gliomagenesis has been recently further strengthened by the frequent occurrence of TERT promoter mutations (TERTp-mut) in gliomas and evidence that the TERT SNP genetic rs2736100 influences glioma risk. 25314060

2014

dbSNP: rs2736100
rs2736100
G 0.900 GeneticVariation GWASCAT We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009