|
rs115303435
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The glioma subgroup analyses showed that the causal variants (rs6062302 and rs115303435) may be associated with increased risk of glioma</span> regardless of histological grades and molecular alterations.
|
30462709 |
2018 |
|
rs6062302
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The glioma subgroup analyses showed that the causal variants (rs6062302 and rs115303435) may be associated with increased risk of glioma regardless of histological grades and molecular alterations.
|
30462709 |
2018 |
|
rs2236507
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple susceptibility loci for glioma.
|
26424050 |
2015 |
|
rs4809324
|
|
C |
0.800 |
GeneticVariation |
GWASDB |
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|
19578366 |
2009 |
|
rs4809324
|
|
C |
0.800 |
GeneticVariation |
GWASCAT |
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|
19578366 |
2009 |
|
rs2297440
|
|
C |
0.820 |
GeneticVariation |
GWASCAT |
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.
|
29743610 |
2018 |
|
rs2297440
|
|
C |
0.820 |
GeneticVariation |
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
rs2297440
|
|
|
0.820 |
GeneticVariation |
BEFREE |
This meta-analysis demonstrates that the RTEL1 rs2297440 polymorphism plays a moderate, but significant role in the risk of gli</span>oma.
|
26939676 |
2016 |
|
rs2297440
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Two single variants, the genotypes of "GG" of rs6010620 and "CC" of rs2297440</span> (rs6010620 and rs2297440) in the RTEL1 gene, together with two haplotypes of GCT and ATT, were identified to be associated with glioma development.
|
23683922 |
2013 |
|
rs2297440
|
|
|
0.820 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The rs6010620 (RTEL1), rs4977756 (CDKN2A/B), and rs498872 (PHLDB1) are associated with glioma risk in the Portuguese population and these data may contribute to understanding gliomas etiology.
|
31721021 |
2020 |
|
rs6010620
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility.
|
30714141 |
2019 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25).
|
26243184 |
2016 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The current meta-analysis suggested that the rs6010620 polymorphism in the RTEL1 gene might increase risk of glioma.
|
25227808 |
2014 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Overall, there was a significant association between RTEL1 rs6010620 polymorphism and glioma risk in all fo</span>ur genetic models (GG vs. AA: OR=1.87, 95 % CI=1.60-2.18, P heterogeneity=0.552; GA vs. AA: OR=1.30, 95 % CI=1.16-1.46, P heterogeneity=0.495; dominant model-GG+GA vs. AA: OR=1.46, 95 % CI=1.31-1.63, P heterogeneity=0.528; recessive model-GG vs. GA+AA: OR=1.36, 95 % CI=1.27-1.46, P heterogeneity=0.093).
|
24523019 |
2014 |
|
rs6010620
|
|
G |
0.900 |
GeneticVariation |
GWASDB |
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
|
24908248 |
2014 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the RTEL1 rs6010620 polymorphism may be a risk factor for glioma.
|
25556444 |
2014 |
|
rs6010620
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
|
24908248 |
2014 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
After Bonferroni correction for multiple comparisons, only one marker was statistically significantly associated with glioma risk, rs6010620 (ORtrend for the minor (A) allele, 0.39; 95% CI: 0.25-0.61; Bonferroni adjusted ptrend , 1.7 × 10(-4) ).
|
23115063 |
2013 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Four of the five SNPs previously reported by others were statistically significantly associated with increased risk of glioma in our study (rs2736100, rs4295627, rs4977756, and rs6010620); rs498872 was not associated with glioma in our study.
|
23903690 |
2013 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Case-control analyses stratified into 4 molecular classes (defined by 1p-19q status, IDH mutation, and EGFR amplification) showed an association of rs4295627 and rs498872 with IDH-mutated gliomas (P < 10(-3)) and rs2736100 and rs6010620 with IDH wild-type gliomas (P < 10(-3) and P = .03).
|
23161787 |
2013 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Two single variants, the genotypes of "GG" of rs</span>6010620 and "CC" of rs2297440 (rs6010620</span> and r</span>s2297440) in the RTEL1 gene, together with two haplotypes of GCT and ATT, were identified to be associated with glioma development.
|
23683922 |
2013 |
|
rs6010620
|
|
G |
0.900 |
GeneticVariation |
GWASDB |
Genome-wide association study of glioma and meta-analysis.
|
22886559 |
2012 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Genome-wide association studies have identified the susceptibility single nucleotide polymorphisms (SNPs) of glioma at chromosome 20q13.33, and the replication study conducted among Chinese Han population also confirmed the susceptibility locus rs6010620 is located in this region.
|
22387365 |
2012 |
|
rs6010620
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Genome-wide association study of glioma and meta-analysis.
|
22886559 |
2012 |