rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Thus, there is limited evidence for the association between the</span> TP53 Arg72Pro polymorphism and risk of glioma, and more studies are needed to provide a more comprehensive assessment of the association in Asians.
|
24046089 |
2014 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma.
|
23096687 |
2012 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In this first assessment of the role of TP53 Arg72Pro polymorphism in a large series of Portuguese glioma tumors, no association was observed with glioma susceptibility or overall survival, except for patients submitted to adjuvant therapy.
|
18068527 |
2008 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These findings suggest that the pri-miR-34b/c rs4938723CC and TP53 Arg72-Pro polymorphisms may be associated with the risk of glioma.
|
30319976 |
2018 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In conclusion, our meta-analysis, based on the combined data from published papers before May 2013, reveals no evidence for significant association between p53 Arg72Pro polymorphism and glioma risk.
|
24488625 |
2014 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Our data suggest that TP53 Pro47Ser and Arg72Pro SNPs are not involved either in susceptibility to developing gliomas or in patient survival, at least in the Brazilian population.
|
18393224 |
2008 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In stratified analyses by ethnicity, source of controls, and glioma subtypes, the p53 codon 72 Arg/Pro polymorphism did not alter the risk for glioma in population-based, hospital-based, astrocytoma, and oligodendroglioma studies among Caucasian.
|
23860773 |
2013 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The codon 72 variant (rs1042522) and rs1642785 polymorphisms possibly poses risk to glioma development in Indian population.
|
21115003 |
2011 |
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In stratified analyses by ethnicity, source of controls, and glioma subtypes, the p53 codon 72 Arg/Pro polymorphism did not alter the risk for glioma in population-based, hospital-based, astrocytoma, and oligodendroglioma studies among Caucasian.
|
23860773 |
2013 |
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In conclusion, our meta-analysis, based on the combined data from published papers before May 2013, reveals no evidence for significant association between p53 Arg72Pro polymorphism and glioma risk.
|
24488625 |
2014 |
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In this first assessment of the role of TP53 Arg72Pro polymorphism in a large series of Portuguese glioma tumors, no association was observed with glioma susceptibility or overall survival, except for patients submitted to adjuvant therapy.
|
18068527 |
2008 |
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
These findings suggest that the pri-miR-34b/c rs4938723CC and TP53 Arg72-Pro polymorphisms may be associated with the risk of glioma.
|
30319976 |
2018 |
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our data suggest that TP53 Pro47Ser and Arg72Pro SNPs are not involved either in susceptibility to developing gliomas or in patient survival, at least in the Brazilian population.
|
18393224 |
2008 |
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Thus, there is limited evidence for the association between the</span> TP53 Arg72Pro polymorphism and risk of glioma, and more studies are needed to provide a more comprehensive assessment of the association in Asians.
|
24046089 |
2014 |
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma.
|
23096687 |
2012 |
rs121912660
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our observations indicate that the R280T mutation of p53 regulates the proliferation of human glioma cells related to the GSK-3β/PTEN pathway.
|
22999923 |
2012 |
rs1625895
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six hundred and eighty glioma cases (298 glioblastoma (GBM)), 503 meningioma cases, and 1555 controls recruited in the Nordic-UK Interphone study, were analysed in association with three polymorphisms in p53 (rs2287499, rs1042533, rs1625895) and five polymorphisms in ATM ( rs228599, rs3092992, rs664143, rs170548, rs3092993).
|
17151932 |
2007 |
rs1642785
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The codon 72 variant (rs1042522) and rs1642785 polymorphisms possibly poses risk to glioma development in Indian population.
|
21115003 |
2011 |
rs1800371
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data suggest that TP53 Pro47Ser and Arg72Pro SNPs are not involved either in susceptibility to developing gliomas or in patient survival, at least in the Brazilian population.
|
18393224 |
2008 |
rs28934575
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This analysis of H3-G34R mutant fission yeast provides mechanistic insight into how G34R mutation may promote genomic instability in glioma.
|
28718400 |
2017 |
rs35850753
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple susceptibility loci for glioma.
|
26424050 |
2015 |
rs55819519
|
|
|
0.070 |
GeneticVariation |
BEFREE |
IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.
|
28427200 |
2017 |
rs55819519
|
|
|
0.070 |
GeneticVariation |
BEFREE |
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.
|
30760578 |
2019 |
rs55819519
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Interestingly, non-p.R132H mutations segregate in distinct histological and molecular subtypes of glioma.
|
20077503 |
2010 |
rs55819519
|
|
|
0.070 |
GeneticVariation |
BEFREE |
This case suggests that 1p/19q co-deletion may rarely precede IDH1 mutations or that IDH1 mutations may be secondarily lost, as demonstrated by IDH1-R132H positive and negative cells in a glioma with diffuse 1p/19q co-deletion.
|
25907263 |
2016 |