Gene: CCDC26 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs55705857
rs55705857
CCDC26
0.760 GeneticVariation BEFREE Analysis by glioma subtype showed the association with rs55705857 confined to non-glioblastoma multiforme (non-GBM) tumours (P = 1.07 × 10(-67)). 23399484

2013
dbSNP: rs4295627
rs4295627
CCDC26
0.900 GeneticVariation BEFREE Case-control analyses stratified into 4 molecular classes (defined by 1p-19q status, IDH mutation, and EGFR amplification) showed an association of rs4295627 and rs498872 with IDH-mutated gliomas (P < 10(-3)) and rs2736100 and rs6010620 with IDH wild-type gliomas (P < 10(-3) and P = .03). 23161787

2013
dbSNP: rs4295627
rs4295627
CCDC26
0.900 GeneticVariation GWASCAT Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs4295627
rs4295627
CCDC26
0.900 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs891835
rs891835
CCDC26
0.810 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs6470745
rs6470745
CCDC26
0.720 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs10464870
rs10464870
CCDC26
0.700 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs12544799
rs12544799
CCDC26
0.700 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs16904140
rs16904140
CCDC26
0.700 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs4636162
rs4636162
CCDC26
0.700 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs6985166
rs6985166
CCDC26
0.700 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs9656979
rs9656979
CCDC26
0.700 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs4295627
rs4295627
CCDC26
0.900 GeneticVariation BEFREE Genome-wide association data have identified common genetic variants at 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A-CDKN2B), 11q23.3 (rs498872, PHLDB1), and 20q13.33 (rs6010620, RTEL1) as determinants of glioma risk. 20462933

2010
dbSNP: rs4295627
rs4295627
CCDC26
0.900 GeneticVariation BEFREE Genome-wide association studies have recently identified single-nucleotide polymorphisms (SNP) in five loci at 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A/CDKN2B), 20q13.33 (rs6010620, RTEL1), and 11q23.3 (rs498872, PHLDB1) to be associated with glioma risk. 20847058

2010
dbSNP: rs891835
rs891835
CCDC26
G 0.810 GeneticVariation GWASDB Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009
dbSNP: rs891835
rs891835
CCDC26
G 0.810 GeneticVariation GWASCAT Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009
dbSNP: rs6470745
rs6470745
CCDC26
0.720 GeneticVariation GWASDB Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009
dbSNP: rs10464870
rs10464870
CCDC26
G 0.700 GeneticVariation GWASDB Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009
dbSNP: rs16904140
rs16904140
CCDC26
0.700 GeneticVariation GWASDB Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009
dbSNP: rs55705857
rs55705857
CCDC26
G 0.760 GeneticVariation GWASCAT Genome-wide association study identifies multiple susceptibility loci for glioma. 26424050

2015
dbSNP: rs55705857
rs55705857
CCDC26
G 0.760 GeneticVariation GWASCAT Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. 28346443

2017
dbSNP: rs55705857
rs55705857
CCDC26
0.760 GeneticVariation BEFREE IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. 27282637

2016
dbSNP: rs55705857
rs55705857
CCDC26
0.760 GeneticVariation BEFREE IDH1/2 mutated glioma has been associated with a germline risk variant, the rs55705857 G allele. 30823903

2019
dbSNP: rs4295627
rs4295627
CCDC26
0.900 GeneticVariation BEFREE In particular, both homozygous GG (P = 1.91 × 10, OR1 = 2.01) and heterozygous GT (P = 7.75 × 10, OR2 = 1.35) genotypes of rs4295627 were associated with glioma risk. 31277128

2019
dbSNP: rs891835
rs891835
CCDC26
0.810 GeneticVariation BEFREE In sub-group analysis, we found that rs891835 and rs6470745 increased the risk of glioma in Europeans and Caucasians. 30778791

2019