rs121913500
|
|
|
0.800 |
GeneticVariation |
BEFREE |
• SWI-LIV is significantly increased in high-grade and IDH1-R132H negative gliomas.
|
27300198 |
2017 |
rs145619195
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Whereas, rs145619195 CT genotype might weaken the susceptibility (OR 0.63, p = 0.024) and prognosis (HR 0.20, p = 0.025) of glioma.
|
30536196 |
2019 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Whereas both H3F3A K27M and BRAF V600E have been reported as poor prognostic markers in pediatric glioma, our case, along with several other reported cases, suggests that the coexistence of these two mutations might not indicate poor prognosis.
|
31254135 |
2019 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Whereas both H3F3A K27M and BRAF V600E have been reported as poor prognostic markers in pediatric glioma, our case, along with several other reported cases, suggests that the coexistence of these two mutations might not indicate poor prognosis.
|
31254135 |
2019 |
rs1057519903
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Whereas both H3F3A K27M and BRAF V600E have been reported as poor prognostic markers in pediatric glioma, our case, along with several other reported cases, suggests that the coexistence of these two mutations might not indicate poor prognosis.
|
31254135 |
2019 |
rs10764901
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When the rs10764901 AG and AA genotypes were pooled for analysis, a significantly decreased risk of glioma was also found (OR, 0.63; 95% CI, 0.43-0.93; <i>P</i>=0.021).
|
30310321 |
2018 |
rs3212227
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When gene-gene interactions were examined, carriers at both loci rs2243115 TG/GG and rs3212227 AC/CC had a 2.62-fold increased risk of glioma compared with those with rs2243115 TT and rs3212227 AC/CC genotypes (OR=2.62, 95% CI, 1.05-6.50).
|
22011063 |
2012 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We were unable to find other examples of glial tumors in public databases with this rare BRAF V600D mutation.
|
27860162 |
2017 |
rs11079041
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We undertook a case-control study to analyze two STAT5 polymorphisms (STAT5a rs11079041 and STAT5b rs2293157) in a Han Chinese population, by extraction of genomic DNA from the peripheral blood of 328 patients with glioma and 342 control participants, and performed STAT5 genotyping using DNA sequencing.
|
24878107 |
2014 |
rs4253079
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We suggest a possible novel association between rs4253079 and survival in this group of patients with low-grade and anaplastic gliomas that needs confirmation in larger datasets.
|
21643987 |
2011 |
rs1057519902
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation.
|
31139567 |
2019 |
rs1553260624
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation.
|
31139567 |
2019 |
rs121913500
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We report that glioma cells showing the IDH1(R132H) mutation become rapidly and spontaneously senescent in vitro.
|
24922649 |
2014 |
rs2910164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We provide novel data suggesting rs2910164 genotype may contribute to glioma susceptibility and outcome.
|
21744077 |
2011 |
rs699473
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed increased risk of glioma (odds ratio [OR](CT/CC)=1.3; 95% confidence interval [95% CI], 1.0-1.7) and meningioma (OR(CT/CC)=1.7; 95% CI, 1.1-2.7) with the C variant of SOD3 rs699473.
|
18682580 |
2008 |
rs121913499
|
|
|
0.720 |
GeneticVariation |
BEFREE |
We newly established an anti-IDH1-R132S-specific mAb SMab-1 for use in diagnosis of mutation-bearing gliomas.
|
21352804 |
2011 |
rs773919809
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the effect of typical polymorphisms of MTHFR (C677T and A1298C) on MGMT methylation based on different serum folate levels in patients with glioma from Northeast China.
|
24301776 |
2013 |
rs1468727
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We identified two susceptibility tSNPs in the EGFR gene that were potentially associated with an increased risk of glioma (rs730437, p = 0.016; OR: 1.32; 95%CI: 1.05-1.66 and rs1468727, p = 0.008; OR: 1.31; 95%CI: 1.04-1.65).
|
22662167 |
2012 |
rs730437
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We identified two susceptibility tSNPs in the EGFR gene that were potentially associated with an increased risk of glioma (rs730437, p = 0.016; OR: 1.32; 95%CI: 1.05-1.66 and rs1468727, p = 0.008; OR: 1.31; 95%CI: 1.04-1.65).
|
22662167 |
2012 |
rs498872
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).
|
19578367 |
2009 |
rs498872
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).
|
19578367 |
2009 |
rs498872
|
|
T |
0.900 |
GeneticVariation |
GWASDB |
We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).
|
19578367 |
2009 |
rs6010620
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).
|
19578367 |
2009 |
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).
|
19578367 |
2009 |
rs6010620
|
|
G |
0.900 |
GeneticVariation |
GWASDB |
We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).
|
19578367 |
2009 |