Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913500
rs121913500
0.800 GeneticVariation BEFREE • SWI-LIV is significantly increased in high-grade and IDH1-R132H negative gliomas. 27300198

2017

dbSNP: rs145619195
rs145619195
0.010 GeneticVariation BEFREE Whereas, rs145619195 CT genotype might weaken the susceptibility (OR 0.63, p = 0.024) and prognosis (HR 0.20, p = 0.025) of glioma. 30536196

2019

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE Whereas both H3F3A K27M and BRAF V600E have been reported as poor prognostic markers in pediatric glioma, our case, along with several other reported cases, suggests that the coexistence of these two mutations might not indicate poor prognosis. 31254135

2019

dbSNP: rs121913377
rs121913377
0.100 GeneticVariation BEFREE Whereas both H3F3A K27M and BRAF V600E have been reported as poor prognostic markers in pediatric glioma, our case, along with several other reported cases, suggests that the coexistence of these two mutations might not indicate poor prognosis. 31254135

2019

dbSNP: rs1057519903
rs1057519903
0.050 GeneticVariation BEFREE Whereas both H3F3A K27M and BRAF V600E have been reported as poor prognostic markers in pediatric glioma, our case, along with several other reported cases, suggests that the coexistence of these two mutations might not indicate poor prognosis. 31254135

2019

dbSNP: rs10764901
rs10764901
0.010 GeneticVariation BEFREE When the rs10764901 AG and AA genotypes were pooled for analysis, a significantly decreased risk of glioma was also found (OR, 0.63; 95% CI, 0.43-0.93; <i>P</i>=0.021). 30310321

2018

dbSNP: rs3212227
rs3212227
0.010 GeneticVariation BEFREE When gene-gene interactions were examined, carriers at both loci rs2243115 TG/GG and rs3212227 AC/CC had a 2.62-fold increased risk of glioma compared with those with rs2243115 TT and rs3212227 AC/CC genotypes (OR=2.62, 95% CI, 1.05-6.50). 22011063

2012

dbSNP: rs121913377
rs121913377
0.100 GeneticVariation BEFREE We were unable to find other examples of glial tumors in public databases with this rare BRAF V600D mutation. 27860162

2017

dbSNP: rs11079041
rs11079041
0.010 GeneticVariation BEFREE We undertook a case-control study to analyze two STAT5 polymorphisms (STAT5a rs11079041 and STAT5b rs2293157) in a Han Chinese population, by extraction of genomic DNA from the peripheral blood of 328 patients with glioma and 342 control participants, and performed STAT5 genotyping using DNA sequencing. 24878107

2014

dbSNP: rs4253079
rs4253079
0.010 GeneticVariation BEFREE We suggest a possible novel association between rs4253079 and survival in this group of patients with low-grade and anaplastic gliomas that needs confirmation in larger datasets. 21643987

2011

dbSNP: rs1057519902
rs1057519902
0.010 GeneticVariation BEFREE We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation. 31139567

2019

dbSNP: rs1553260624
rs1553260624
0.010 GeneticVariation BEFREE We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation. 31139567

2019

dbSNP: rs121913500
rs121913500
0.800 GeneticVariation BEFREE We report that glioma cells showing the IDH1(R132H) mutation become rapidly and spontaneously senescent in vitro. 24922649

2014

dbSNP: rs2910164
rs2910164
0.010 GeneticVariation BEFREE We provide novel data suggesting rs2910164 genotype may contribute to glioma susceptibility and outcome. 21744077

2011

dbSNP: rs699473
rs699473
0.010 GeneticVariation BEFREE We observed increased risk of glioma (odds ratio [OR](CT/CC)=1.3; 95% confidence interval [95% CI], 1.0-1.7) and meningioma (OR(CT/CC)=1.7; 95% CI, 1.1-2.7) with the C variant of SOD3 rs699473. 18682580

2008

dbSNP: rs121913499
rs121913499
0.720 GeneticVariation BEFREE We newly established an anti-IDH1-R132S-specific mAb SMab-1 for use in diagnosis of mutation-bearing gliomas. 21352804

2011

dbSNP: rs773919809
rs773919809
0.010 GeneticVariation BEFREE We investigated the effect of typical polymorphisms of MTHFR (C677T and A1298C) on MGMT methylation based on different serum folate levels in patients with glioma from Northeast China. 24301776

2013

dbSNP: rs1468727
rs1468727
0.030 GeneticVariation BEFREE We identified two susceptibility tSNPs in the EGFR gene that were potentially associated with an increased risk of glioma (rs730437, p = 0.016; OR: 1.32; 95%CI: 1.05-1.66 and rs1468727, p = 0.008; OR: 1.31; 95%CI: 1.04-1.65). 22662167

2012

dbSNP: rs730437
rs730437
0.040 GeneticVariation BEFREE We identified two susceptibility tSNPs in the EGFR gene that were potentially associated with an increased risk of glioma (rs730437, p = 0.016; OR: 1.32; 95%CI: 1.05-1.66 and rs1468727, p = 0.008; OR: 1.31; 95%CI: 1.04-1.65). 22662167

2012

dbSNP: rs498872
rs498872
T 0.900 GeneticVariation GWASCAT We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs498872
rs498872
0.900 GeneticVariation BEFREE We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs498872
rs498872
T 0.900 GeneticVariation GWASDB We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs6010620
rs6010620
G 0.900 GeneticVariation GWASCAT We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs6010620
rs6010620
0.900 GeneticVariation BEFREE We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs6010620
rs6010620
G 0.900 GeneticVariation GWASDB We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009