|
rs1005230
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
rs10069690
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.
|
29743610 |
2018 |
|
rs10069690
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple susceptibility loci for glioma.
|
26424050 |
2015 |
|
rs10069690
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.
|
29743610 |
2018 |
|
rs10069690
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
rs10116277
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|
21531791 |
2011 |
|
rs10120688
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|
21531791 |
2011 |
|
rs10131
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, our results suggest that LIG4 rs10131 polymorphism in the DNA repair pathways plays an important role in the risk of glioma in a Chinese population.
|
25973104 |
2015 |
|
rs10131
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Finally, the gene-gene interaction analysis suggested that the three-locus model (rs1805388, rs10131, and rs2075685) was the best model for ligase IV and XRCC4 to have interaction effects on the risk of glioma.
|
27508978 |
2016 |
|
rs10131032
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
rs10165970
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Study distribution by tumor was as follows: breast cancer (n=15), prostate cancer (n=3), pancreatic cancer (n=2), non-Hodgkin's lymphoma (n=2), glioma (n=1), chronic lymphocytic leukemia (n=1), colorectal cancer (n=1), non-small cell lung cancer (n=1) and ovarian cancer (n=1).We identified 10 single nucleotide polymorphisms (SNPs) significantly associated with cancer risk: NPAS2 rs10165970 (mixed and breast cancer shiftworkers), rs895520 (mixed), rs17024869 (breast) and rs7581886 (breast); CLOCK rs3749474 (breast) and rs11943456 (breast); RORA rs7164773 (breast and breast cancer postmenopausal), rs10519097 (breast); RORB rs7867494 (breast cancer postmenopausal), PER3 rs1012477 (breast cancer subgroups) and assessed the level of quality evidence to be intermediate.
|
28177907 |
2017 |
|
rs1034749666
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This case suggests that 1p/19q co-deletion may rarely precede IDH1 mutations or that IDH1 mutations may be secondarily lost, as demonstrated by IDH1-R132H positive and negative cells in a glioma with diffuse 1p/19q co-deletion.
|
25907263 |
2016 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Thus, there is limited evidence for the association between the</span> TP53 Arg72Pro polymorphism and risk of glioma, and more studies are needed to provide a more comprehensive assessment of the association in Asians.
|
24046089 |
2014 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma.
|
23096687 |
2012 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In this first assessment of the role of TP53 Arg72Pro polymorphism in a large series of Portuguese glioma tumors, no association was observed with glioma susceptibility or overall survival, except for patients submitted to adjuvant therapy.
|
18068527 |
2008 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These findings suggest that the pri-miR-34b/c rs4938723CC and TP53 Arg72-Pro polymorphisms may be associated with the risk of glioma.
|
30319976 |
2018 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In conclusion, our meta-analysis, based on the combined data from published papers before May 2013, reveals no evidence for significant association between p53 Arg72Pro polymorphism and glioma risk.
|
24488625 |
2014 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Our data suggest that TP53 Pro47Ser and Arg72Pro SNPs are not involved either in susceptibility to developing gliomas or in patient survival, at least in the Brazilian population.
|
18393224 |
2008 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In stratified analyses by ethnicity, source of controls, and glioma subtypes, the p53 codon 72 Arg/Pro polymorphism did not alter the risk for glioma in population-based, hospital-based, astrocytoma, and oligodendroglioma studies among Caucasian.
|
23860773 |
2013 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The codon 72 variant (rs1042522) and rs1642785 polymorphisms possibly poses risk to glioma development in Indian population.
|
21115003 |
2011 |
|
rs1044129
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study evaluated the role of TYMS (rs1059394, C > T, and rs2847153, G > A), RYR3 (rs1044129, G > A), KIAA0423 (rs1053667, T > C), and GOLGA7 (rs11337, G > T) polymorphisms for assessment of glioma risk and prognosis among the Chinese Han population.
|
31525662 |
2019 |
|
rs1045485
|
|
|
0.020 |
GeneticVariation |
BEFREE |
D302H polymorphism of CASP8 gene may be associated with increased risk of glioma but larger study groups in different ethnic populations are needed to better elucidate the role of CASP8 gene polymorphism in the pathogenesis of primary brain tumors.
|
26359420 |
2016 |
|
rs1045485
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association of CASP8 D302H with glioma risk indicates the importance of inherited variation in the apoptosis pathway in susceptibility to this form of primary brain tumor.
|
18398042 |
2008 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although the C3435T polymorphism does not appear to be associated with other types of glioma, we cannot rule out that this MDR1 polymorphism may be associated with glioblastoma among men.
|
15947495 |
2005 |
|
rs10464870
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|
21531791 |
2011 |