Gene: TERT ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2853676
rs2853676
TERT
0.840 GeneticVariation BEFREE Our study indicates that TERT rs2853676 polymorphisms correlate with glioma survival and recurrence rates in a Chinese population, which suggests that they could potentially serve as prognostic markers in glioma patients. 27655710

2016
dbSNP: rs2853676
rs2853676
TERT
0.840 GeneticVariation BEFREE This meta-analysis suggests that the TERT genetic polymorphism rs2853676 is associated with increased risk of glioma, lung adenocarcinoma and ovarian cancer among Caucasians. 26042809

2015
dbSNP: rs2853676
rs2853676
TERT
0.840 GeneticVariation BEFREE The genotype #GA# for rs1695 was recognized to be a protective genotype for glioma (OR, 0.67; 95% CI, 0.47-0.96; P = 0.027), while the genotype #AG# for rs2853676 was shown to be a risk genotype for glioma (OR, 1.50; 95% CI, 1.05-2.15; P = 0.025). 22795327

2012
dbSNP: rs2853676
rs2853676
TERT
0.840 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs2853676
rs2853676
TERT
A 0.840 GeneticVariation GWASDB Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009
dbSNP: rs2853676
rs2853676
TERT
A 0.840 GeneticVariation GWASCAT Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009
dbSNP: rs10069690
rs10069690
TERT
T 0.700 GeneticVariation GWASCAT Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 29743610

2018
dbSNP: rs10069690
rs10069690
TERT
C 0.700 GeneticVariation GWASCAT Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 29743610

2018
dbSNP: rs10069690
rs10069690
TERT
T 0.700 GeneticVariation GWASCAT Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. 28346443

2017
dbSNP: rs10069690
rs10069690
TERT
T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies multiple susceptibility loci for glioma. 26424050

2015
dbSNP: rs2853677
rs2853677
TERT
0.010 GeneticVariation BEFREE Our results indicate that sequence variants in the region flanking rs2853677 may account for the GWAS and replication signals identified in 5p15.33 for glioma susceptibility in Chinese population; besides, haplotype G-T-A in CLPTM1L also confers a risk to glioma suggesting CLPTM1L is also involved in the etiology of glioma. 22213090

2012
dbSNP: rs2736098
rs2736098
TERT
0.010 GeneticVariation BEFREE Overall, the authors identified 3 susceptibility loci for glioma risk at 20q13.33 (RTEL1 rs6010620 (P = 2.79 × 10(-6))), 11q23.3 (PHLDB1 rs498872 (P = 3.8 × 10(-6))), and 5p15.33 (TERT rs2736100 (P = 3.69 × 10(-4))) in this study population; these loci were also associated with glioblastoma risk (20q13.33: RTEL1 rs6010620 (P = 3.57 × 10(-7)); 11q23.3: PHLDB1 rs498872 (P = 7.24 × 10(-3)); 5p15.33: TERT rs2736100 and TERT rs2736098 (P = 1.21 × 10(-4) and P = 2.84 × 10(-4), respectively)). 21350045

2011