|
rs494560
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Additionally, two novel SNPs (rs2236661 and rs494560) that were independent of rs17749 were significantly associated with glioma risk in a recessive genetic model [P = 1.31×10⁻⁵ and P = 3.32×10⁻⁵, respectively].
|
23300798 |
2012 |
|
rs17749
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, two novel SNPs (rs2236661 and rs494560) that were independent of rs17749 were significantly associated with glioma risk in a recessive genetic model [P = 1.31×10⁻⁵ and P = 3.32×10⁻⁵, respectively].
|
23300798 |
2012 |
|
rs6010620
|
|
|
0.900 |
GeneticVariation |
BEFREE |
After Bonferroni correction for multiple comparisons, only one marker was statistically significantly associated with glioma risk, rs6010620 (ORtrend for the minor (A) allele, 0.39; 95% CI: 0.25-0.61; Bonferroni adjusted ptrend , 1.7 × 10(-4) ).
|
23115063 |
2013 |
|
rs3024994
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
rs2010963
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
rs1005230
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
rs121913500
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Although there are many changes of genes in tumour malignant progression, IDH1 R132H mutation status in glioma progression remained unclear.
|
28928859 |
2017 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although the C3435T polymorphism does not appear to be associated with other types of glioma, we cannot rule out that this MDR1 polymorphism may be associated with glioblastoma among men.
|
15947495 |
2005 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Although this glioma was difficult to clarify, diagnosis of pleomorphic xanthoastrocytoma with anaplastic feature was suggested based on the association of some pathological feature (eosinophilic granular bodies, reticulin network and diffuse CD34 expression) and the BRAF V600E mutation.
|
24857351 |
2014 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Although this glioma was difficult to clarify, diagnosis of pleomorphic xanthoastrocytoma with anaplastic feature was suggested based on the association of some pathological feature (eosinophilic granular bodies, reticulin network and diffuse CD34 expression) and the BRAF V600E mutation.
|
24857351 |
2014 |
|
rs3761121
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among 99 SNPs, five independent susceptibility loci (20-62315594 in RTEL1, 20-62335293 in adenosine diphosphate ribosylation factor-related protein 1, rs3761121 in ZGPAT, rs1058319 in SLC2A4RG and rs5019252 in ZBTB46) were identified for glioma.
|
22387365 |
2012 |
|
rs1058319
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among 99 SNPs, five independent susceptibility loci (20-62315594 in RTEL1, 20-62335293 in adenosine diphosphate ribosylation factor-related protein 1, rs3761121 in ZGPAT, rs1058319 in SLC2A4RG and rs5019252 in ZBTB46) were identified for glioma.
|
22387365 |
2012 |
|
rs5019252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among 99 SNPs, five independent susceptibility loci (20-62315594 in RTEL1, 20-62335293 in adenosine diphosphate ribosylation factor-related protein 1, rs3761121 in ZGPAT, rs1058319 in SLC2A4RG and rs5019252 in ZBTB46) were identified for glioma.
|
22387365 |
2012 |
|
rs55705857
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Analysis by glioma subtype showed the association with rs55705857 confined to non-glioblastoma multiforme (non-GBM) tumours (P = 1.07 × 10(-67)).
|
23399484 |
2013 |
|
rs13181
|
|
|
0.100 |
GeneticVariation |
BEFREE |
And the TT genotype of ERCC2 Lys751Gln polymorphism may decrease the risk of glioma in the Caucasian population.
|
24763305 |
2014 |
|
rs2151280
|
|
|
0.710 |
GeneticVariation |
BEFREE |
ANRIL rs2151280 variant genotype might increase susceptibility of glioma.
|
31489712 |
2019 |
|
rs78378222
|
|
|
0.720 |
GeneticVariation |
BEFREE |
As rs78378222 changes the polyadenylation signal of TP53 leading to impaired 3'-end processing of TP53 mRNA, the SNP has strong plausibility for being directly functional contributing to the aetiological basis of glioma.
|
23571737 |
2013 |
|
rs25490
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As for c.910A>G, the risk of glioma</span> for genotype GG was significantly higher than wild genotype AA (odds ratio (OR) = 1.98, 95% confidence interval (CI) 1.33-2.94, P = 0.001).
|
23918303 |
2014 |
|
rs148611340
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As for c.1779C>G, the genotype GG was statistically associated with the increased risk of glioma compared to wild genotype CC (OR = 1.80, 95% CI 1.17-2.78, P = 0.007).
|
23918303 |
2014 |
|
rs121913500
|
|
|
0.800 |
GeneticVariation |
BEFREE |
As IDH1(R132H) is present in all tumour cells of these slow-growing gliomas, a mutation-specific anti-IDH1(R132H) vaccine may represent a viable novel therapeutic strategy for IDH1(R132H)-mutated tumours.
|
25043048 |
2014 |
|
rs4938723
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association analysis showed that the CC genotype of the pir-miR-34b/c rs4938723 was associated with a significantly decreased risk of glioma compared to the TT genotype (CC vs. TT: adjusted OR = 0.43;95% CI, 0.21-0.87,<i>P</i> = 0.02).
|
30319976 |
2018 |
|
rs1217691063
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association between MTHFR 677C>T polymorphism and risk of gliomas: evidence from a meta-analysis.
|
23765760 |
2013 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma.
|
23096687 |
2012 |
|
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma.
|
23096687 |
2012 |
|
rs878854066
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma.
|
23096687 |
2012 |