DisGeNET - a database of gene-disease associations

Glioma, C0017638

Variant: rs1468727 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1468727

EGFR

0.030

GeneticVariation

BEFREE

We found that the CC genotype of rs1468727 was more common in the glioma group than in the control group (p=0.021).

25514356

2015

dbSNP:

rs1468727

EGFR

0.030

GeneticVariation

BEFREE

We identified two susceptibility tSNPs in the EGFR gene that were potentially associated with an increased risk of glioma (rs730437, p = 0.016; OR: 1.32; 95%CI: 1.05-1.66 and rs1468727, p = 0.008; OR: 1.31; 95%CI: 1.04-1.65).

22662167

2012

dbSNP:

rs1468727

EGFR

0.030

GeneticVariation

BEFREE

Our comprehensive analysis of nine SNPs in eight genes suggests that the rs730437 and rs1468727 in ERGF, rs1799782 in XRCC1 gene, and rs861539 in XRCC3 gene are associated with glioma risk.

23244079

2012