Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Specific single nucleotides polymorphisms (SNPs) rs4977756 (CDKN2A/B), rs6010620 (RTEL1), rs498872 (PHLDB1), rs2736100 (TERT), and rs4295627 (CCDC26) have been associated with glioma susceptibility and are potential risk biomarkers. 31721021

2020

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE In particular, both homozygous GG (P = 1.91 × 10, OR1 = 2.01) and heterozygous GT (P = 7.75 × 10, OR2 = 1.35) genotypes of rs4295627 were associated with glioma risk. 31277128

2019

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE The results of the present study clearly show that the G allele of the rs4295627 polymorphism significantly increases the risk of glioma. 29264887

2017

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25). 26243184

2016

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Thus, our meta-analysis suggests that the rs4295627 SNP is associated with an increased risk of glioma. 26505354

2015

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Case-control analyses stratified into 4 molecular classes (defined by 1p-19q status, IDH mutation, and EGFR amplification) showed an association of rs4295627 and rs498872 with IDH-mutated gliomas (P < 10(-3)) and rs2736100 and rs6010620 with IDH wild-type gliomas (P < 10(-3) and P = .03). 23161787

2013

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Three of the gene variants (rs4295627, a variant of CCDC26; rs4977756, a variant of CDKN2A and CDKN2B; and rs6010620, a variant of RTEL1) were statistically significantly associated with glioma risk in the present population. 21920947

2011

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation GWASCAT Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Genome-wide association data have identified common genetic variants at 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A-CDKN2B), 11q23.3 (rs498872, PHLDB1), and 20q13.33 (rs6010620, RTEL1) as determinants of glioma risk. 20462933

2010

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Our group identified 5 risk loci for glioma susceptibility (TERT rs2736100, CCDC26 rs4295627, CDKN2A/CDKN2B rs4977756, RTEL1 rs6010620, and PHLDB1 rs498872). 20212223

2010

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Genome-wide association studies have recently identified single-nucleotide polymorphisms (SNP) in five loci at 5p15.33 (rs2736100, TERT), 8q24.21 (rs4295627, CCDC26), 9p21.3 (rs4977756, CDKN2A/CDKN2B), 20q13.33 (rs6010620, RTEL1), and 11q23.3 (rs498872, PHLDB1) to be associated with glioma risk. 20847058

2010

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs4295627
rs4295627
G 0.900 GeneticVariation GWASDB We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs4295627
rs4295627
G 0.900 GeneticVariation GWASCAT We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009

dbSNP: rs891835
rs891835
0.810 GeneticVariation BEFREE In sub-group analysis, we found that rs891835 and rs6470745 increased the risk of glioma in Europeans and Caucasians. 30778791

2019

dbSNP: rs891835
rs891835
0.810 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011

dbSNP: rs891835
rs891835
G 0.810 GeneticVariation GWASDB Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009

dbSNP: rs891835
rs891835
G 0.810 GeneticVariation GWASCAT Genome-wide association study identifies five susceptibility loci for glioma. 19578367

2009

dbSNP: rs55705857
rs55705857
0.760 GeneticVariation BEFREE IDH1/2 mutated glioma has been associated with a germline risk variant, the rs55705857 G allele. 30823903

2019

dbSNP: rs55705857
rs55705857
0.760 GeneticVariation BEFREE Of the 6 variants located in 8q24, 2 have strong significant associations with the risk of glioma, including rs4295627 (P = .003, odds ratio [OR] = 1.21), rs55705857 (P = 2.31 × 10, OR = 3.54). 31277128

2019

dbSNP: rs55705857
rs55705857
0.760 GeneticVariation BEFREE Taken into consideration the limitations of this study, the present findings suggest a possible participation of rs891835, rs6470745, and rs55705857 as risk factors to develop glioma. 30778791

2019

dbSNP: rs55705857
rs55705857
G 0.760 GeneticVariation GWASCAT Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 29743610

2018

dbSNP: rs55705857
rs55705857
G 0.760 GeneticVariation GWASCAT Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. 28346443

2017

dbSNP: rs55705857
rs55705857
0.760 GeneticVariation BEFREE IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. 27282637

2016