Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Specific single nucleotides polymorphisms (SNPs) rs4977756 (CDKN2A/B), rs6010620 (RTEL1), rs498872 (PHLDB1), rs2736100 (TERT), and rs4295627 (CCDC26) have been associated with glioma susceptibility and are potential risk biomarkers. 31721021

2020

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Specific single nucleotides polymorphisms (SNPs) rs4977756 (CDKN2A/B), rs6010620 (RTEL1), rs498872 (PHLDB1), rs2736100 (TERT), and rs4295627 (CCDC26) have been associated with glioma susceptibility and are potential risk biomarkers. 31721021

2020

dbSNP: rs4977756
rs4977756
0.900 GeneticVariation BEFREE It was found that the AG and GG genotypes of the rs4977756 (CDKN2A/B) were associated with an increased risk of gliomas (OR 1.85 and OR 2.38) and glioblastomas (OR 2.77 and OR 3.94). 31721021

2020

dbSNP: rs498872
rs498872
0.900 GeneticVariation BEFREE In addition, the genotype AA of the rs498872 (PHLDB1) was associated with poor overall survival of gliomas patients (AA vs. GA, p = 0.037). 31721021

2020

dbSNP: rs6010620
rs6010620
0.900 GeneticVariation BEFREE The rs6010620 (RTEL1), rs4977756 (CDKN2A/B), and rs498872 (PHLDB1) are associated with glioma risk in the Portuguese population and these data may contribute to understanding gliomas etiology. 31721021

2020

dbSNP: rs2736100
rs2736100
C 0.900 GeneticVariation GWASCAT Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility. 30714141

2019

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE In particular, both homozygous GG (P = 1.91 × 10, OR1 = 2.01) and heterozygous GT (P = 7.75 × 10, OR2 = 1.35) genotypes of rs4295627 were associated with glioma risk. 31277128

2019

dbSNP: rs498872
rs498872
A 0.900 GeneticVariation GWASCAT Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility. 30714141

2019

dbSNP: rs498872
rs498872
0.900 GeneticVariation BEFREE Our findings suggested that the rs498872 polymorphism may serve as a potential genetic biomarker of glioma in both Asians and Caucasians. 30684220

2019

dbSNP: rs6010620
rs6010620
G 0.900 GeneticVariation GWASCAT Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility. 30714141

2019

dbSNP: rs4977756
rs4977756
0.900 GeneticVariation BEFREE We hypothesized that CCDKN2A/B rs1063192 and rs4977756 and also the long noncoding RNA (lncRNA) CDKN2BAS rs2157719 glioma susceptibility polymorphisms identified by genome-wide association studies may contribute to medulloblastoma predisposition. 29314442

2018

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE The results of the present study clearly show that the G allele of the rs4295627 polymorphism significantly increases the risk of glioma. 29264887

2017

dbSNP: rs498872
rs498872
0.900 GeneticVariation BEFREE In conclusion, this study found that PHLDB1 rs498872 polymorphism was significantly associated with glioma risk in Chinese Han population. 28886307

2017

dbSNP: rs2736100
rs2736100
0.900 GeneticVariation BEFREE Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25). 26243184

2016

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25). 26243184

2016

dbSNP: rs4977756
rs4977756
0.900 GeneticVariation BEFREE Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25). 26243184

2016

dbSNP: rs4977756
rs4977756
0.900 GeneticVariation BEFREE The CDKN2A/B rs4977756 polymorphism is obvious increase the risk of glioma in Caucasians. 26577493

2016

dbSNP: rs4977756
rs4977756
0.900 GeneticVariation BEFREE In conclusion, we found an association between rs1412829 and rs4977756 (9p21.3, CDKN2B-AS1) and global DNA methylation pattern in glioma, for which a trend was seen also in the TCGA glioblastoma dataset. 27780202

2016

dbSNP: rs498872
rs498872
0.900 GeneticVariation BEFREE Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25). 26243184

2016

dbSNP: rs6010620
rs6010620
0.900 GeneticVariation BEFREE Results showed that seven hot loci were all associated with increased risk of glioma (rs2736100, OR = 1.28, 95 %CI = 1.23-1.32; rs4295627, OR = 1.34, 95 %CI = 1.21-1.47; rs4977756, OR = 1.24, 95 %CI = 1.20-1.28; rs498872, OR = 1.24, 95 %CI = 1.15-1.33; rs6010620, OR = 1.29, 95 %CI = 1.24-1.35; rs11979158: OR = 1.18, 95 %CI = 1.10-1.25; rs2252586: OR = 1.18, 95 %CI = 1.10-1.25). 26243184

2016

dbSNP: rs4295627
rs4295627
0.900 GeneticVariation BEFREE Thus, our meta-analysis suggests that the rs4295627 SNP is associated with an increased risk of glioma. 26505354

2015

dbSNP: rs498872
rs498872
0.900 GeneticVariation BEFREE Our meta-analysis suggested that rs498872 polymorphism was associated with increased risk of glioma. 24935770

2015

dbSNP: rs498872
rs498872
0.900 GeneticVariation BEFREE We found 1.17-1.34-fold increased risk of glioma associated with rs498872 genotypes (OR 1.34, 95% CI 1.22-1.46; OR 1.24, 95% CI 1.14-1.35; OR 1.20, 95% CI 1.10-1.31; OR 1.17, 95% CI 1.08-1.27). 25182002

2015

dbSNP: rs2736100
rs2736100
C 0.900 GeneticVariation GWASDB Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 24908248

2014

dbSNP: rs2736100
rs2736100
C 0.900 GeneticVariation GWASCAT Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 24908248

2014