Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.010 | GeneticVariation | BEFREE | The CYP2B6*9 and ABCB1 C3435T polymorphisms alter the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide in glomerulonephritis. | 22380717 | 2012 |
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0.010 | GeneticVariation | BEFREE | Therefore, we analysed the distribution of the functional MCP-1 -2518 A > G (rs 1024611) and 1 beta 1,3-galactosyltransferase (C1GalT1) 1365 A > G (rs1047763) polymorphic variants in patients with primary GN (n = 144) and controls (n = 437) in a sample of the Polish population. | 22203484 | 2012 |
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0.010 | GeneticVariation | BEFREE | In addition to 3 patients with aHUS, the A304V mutation was identified in 1 patient each with fatal Stx-HUS, the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome, and glomerulonephritis with C3 deposits. | 17914026 | 2008 |
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0.010 | GeneticVariation | BEFREE | FcalphaRI activation in FcalphaRI(wt), but not in FcalphaRI(R209L), Tg mice resulted in marked inflammation with severe proteinuria and leukocyte infiltration in spontaneous IgAN or anti-glomerular basement membrane Ab-induced GN models. | 17393381 | 2007 |
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0.020 | GeneticVariation | BEFREE | The association between therapeutic outcomes and VEGF G-1154A and C-936T gene polymorphisms in patients with glomerulonephritis. | 24673399 | 2014 |
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0.020 | GeneticVariation | BEFREE | Finally, we have not proved any significant influence of the polymorphisms at positions -2578 C/A and -1154 G/A of the vascular endothelial growth factor gene promoter on the progression of chronic glomerulonephritides even though our study suggests a negative effect of CC genotype of -2578 C/A polymorphism on the clinical course of minimal change disease/focal segmental glomerulosclerosis. | 21978756 | 2011 |
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G | 0.700 | GeneticVariation | GWASDB | A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. | 20668430 | 2010 |
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A | 0.700 | GeneticVariation | CLINVAR |