Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The AGT (M268T) genotypes were distributed in IgAN as CC 61.9%, CT 34.8%, and TT 3.2%, while in controls CC 64.1%, CT 31.3%, and TT 4.6%. 26588355

2015

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE rs699 in the AGT gene and rs5186 in the ATR1 gene were not associated with the risk and clinical outcomes of IgAN. 26588355

2015

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE In conclusion, AGT M235T gene polymorphism may not be correlated with IgAN susceptibility in overall populations, Caucasians and Asians. 24344785

2014

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The angiotensin I-converting enzyme (ACE) gene insertion/deletion (I/D), the angiotensinogen (AGT) gene, M235T, the aldosterone synthase (CYP11B2) gene, C-344T, and the angiotensin II type 1 receptor (AT1R) gene, A1166C, have been shown to be associated with IgA nephropathy (IgAN) and its progression. 21163122

2010

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Our results suggest that the AGT M235T polymorphism is associated with the progression of IgAN in Korean male patients. 19729965

2009

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Our results suggest that angiotensinogen-M235T polymorphism is an important marker of progression in IgA nephropathy in Caucasian patients, especially when analyzed in combination with ACE-I/D polymorphism. 15031629

2004

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The angiotensin I-converting enzyme (ACE) gene insertion/deletion (I/D), the angiotensinogen (AGT) gene, M235T, and the angiotensin II type 1 receptor (ATR) gene, A1166C, polymorphisms have been associated with IgA nephropathy (IgAN) and its progression. 15504143

2004

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE This study provides evidence that the M235T and A(-20)C genotype of AGT can influence the therapeutic efficacy of a RAS blockade on the renal survival in IgAN. 12911556

2003

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE To evaluate the role of AGT polymorphisms in the progression of IgA nephropathy (IgAN), we analyzed the association of A(-20)C and M235T polymorphisms with renal prognosis in histologically-proven IgAN patients using the Kaplan-Meier method and Cox proportional hazards regression model. 12164881

2002

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE We identified the M235T polymorphism of the angiotensinogen (AGT) gene, the I/D polymorphisms of the angiotensin-converting enzyme (ACE) gene, and the A1166C polymorphism of the angiotensin II type 1 receptor gene in 95 Japanese children with IgA nephropathy and 99 healthy Japanese adults. 11354780

2001

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Deletion/insertion polymorphism (D/I) of the angiotensin I converting enzyme gene, M235T polymorphism (T/M) of the angiotensinogen gene and A1166C polymorphism (C/A) of the angiotensin II type 1 receptor gene were determined in 274 Caucasian men with biopsy-proven IgAN (n = 86, 112, and 76 in stages 1, 2, and 3, respectively). 11053482

2000

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE We examined whether the M235T polymorphism of the angiotensinogen (AGT) gene, the insertion/deletion polymorphism of the angiotensin-converting enzyme (ACE) gene, and the A1166--> C polymorphism of the angiotensin II type 1 receptor gene may be associated with disease progression in 168 Caucasian patients with IgA nephropathy. 9259580

1997