|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C gene polymorphisms are associated with the risk of patent ductus arteriosus (PDA) congenital heart defects.
|
24566197 |
2014 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Congenital heart defects (CHD) are the third leading cause of death in children <1 year of age in Mexico where there is a high prevalence of the 677C → T polymorphism of the MTHFR gene.
|
22660520 |
2013 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Maternal MTHFR C677T polymorphism and congenital heart defect risk in the Chinese Han population: a meta-analysis.
|
24338416 |
2013 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MTHFR C677T polymorphism and risk of congenital heart defects: evidence from 29 case-control and TDT studies.
|
23536781 |
2013 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta analysis of the association between MTHFR C677T polymorphism and the risk of congenital heart defects.
|
22175539 |
2012 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Evaluation of C677T and A1298C polymorphisms of the MTHFR gene as maternal risk factors for Down syndrome and congenital heart defects.
|
19725133 |
2009 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of congenital cardiac defects and the C677T methylenetetrahydrofolate reductase polymorphism.
|
17510921 |
2007 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The MTHFR 677C->T polymorphism and the risk of congenital heart defects: a literature review and meta-analysis.
|
17965089 |
2007 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To observe the association of MTHFR gene C677T locus polymorphism with occurrence of congenital heart defects (CHDs), 21 patients with atrial septal defect (ASD), 35 patients with patent ductus arteriosus (PDA), one patient with both conditions combined, and their biological parents were collected as the case group.
|
16373366 |
2006 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Maternal MTHFR 677C>T is a risk factor for congenital heart defects: effect modification by periconceptional folate supplementation.
|
16524890 |
2006 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study was undertaken to investigate the association between congenital heart defects (CHD), and maternal homocysteine, smoking, and the MTHFR 677 C>T polymorphism.
|
16389035 |
2006 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Fifty percent of these isolated congenital cardiac defects were associated with either the C677T MTHFR mutation or elevated amniotic fluid homocysteine levels, or both.
|
11303187 |
2001 |
|
rs1801394
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Parental Genetic Variants, MTHFR 677C>T and MTRR 66A>G, Associated Differently with Fetal Congenital Heart Defect.
|
28758112 |
2017 |
|
rs1801394
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Association between methionine synthase reductase A66G polymorphism and the risk of congenital heart defects: evidence from eight case-control studies.
|
24913415 |
2014 |
|
rs1801394
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A66G and C524T polymorphisms of the methionine synthase reductase gene are associated with congenital heart defects in the Chinese Han population.
|
22057956 |
2011 |
|
rs1801394
|
|
|
0.040 |
GeneticVariation |
BEFREE |
MTRR 66A>G polymorphism in relation to congenital heart defects.
|
17087642 |
2006 |
|
rs2236225
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Relationship of the MTHFD1 (rs2236225), eNOS (rs1799983), CBS (rs2850144) and ACE (rs4343) gene polymorphisms in a population of Iranian pediatric patients with congenital heart defects.
|
28865601 |
2017 |
|
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
MTHFR A1298C polymorphisms reduce the risk of congenital heart defects: a meta-analysis from 16 case-control studies.
|
29202788 |
2017 |
|
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C gene polymorphisms are associated with the risk of patent ductus arteriosus (PDA) congenital heart defects.
|
24566197 |
2014 |
|
rs2236225
|
|
|
0.030 |
GeneticVariation |
BEFREE |
MTHFD1 p.R653Q has been proposed as a risk factor for neural tube defects (NTDs), congenital heart defects (CHDs) and pregnancy losses.
|
23704330 |
2013 |
|
rs2236225
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects.
|
18767138 |
2009 |
|
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Evaluation of C677T and A1298C polymorphisms of the MTHFR gene as maternal risk factors for Down syndrome and congenital heart defects.
|
19725133 |
2009 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Increased risk for congenital heart defects in children carrying the ABCB1 Gene C3435T polymorphism and maternal periconceptional toxicants exposure.
|
23874772 |
2013 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect.
|
21183151 |
2011 |
|
rs12921862
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic Variants at the rs4720169 Locus of <i>TBX20</i> and the rs12921862 Locus of <i>AXIN1</i> May Increase the Risk of Congenital Heart Defects in the Mexican Population: A Pilot Study.
|
31524541 |
2019 |