Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799983
rs1799983
0.060 GeneticVariation BEFREE Heart failure and endothelial nitric oxide synthase G894T gene polymorphism frequency variations within ancestries. 28554876

2018

dbSNP: rs1042713
rs1042713
0.040 GeneticVariation BEFREE Arginine 16 glycine beta2-adrenoceptor polymorphism and cardiovascular structure and function in patients with heart failure. 17336757

2007

dbSNP: rs1320702652
rs1320702652
0.040 GeneticVariation BEFREE C34T AMPD1 polymorphism may be associated with reduced frequency of obesity in CAD patients and of hyperglycaemia and diabetes in both CAD and HF patients. 18855224

2009

dbSNP: rs121918080
rs121918080
TTR
0.010 GeneticVariation BEFREE A 47-year-old man started developing severe diarrhea and weight loss at age 41 years, followed by urinary incontinence, autonomic-nervous-system abnormalities and serious heart failure; the diagnosis of FAP (ATTR Ser50Ile) was made on the basis of genetic, histochemical and immunohistochemical analysis. 10834537

2000

dbSNP: rs10927887
rs10927887
0.020 GeneticVariation BEFREE A CLCNKA polymorphism (rs10927887; p.Arg83Gly) previously linked to heart failure is associated with the estimated glomerular filtration rate in the RENASTUR cohort. 23850580

2013

dbSNP: rs1800730
rs1800730
0.010 GeneticVariation BEFREE A rare S65C mutation and a novel A271S mutation were also found in this study; the latter patient had 4+ iron in the liver and later developed heart failure with cardiac iron. 20208481

2010

dbSNP: rs1337916669
rs1337916669
0.010 GeneticVariation BEFREE A rare S65C mutation and a novel A271S mutation were also found in this study; the latter patient had 4+ iron in the liver and later developed heart failure with cardiac iron. 20208481

2010

dbSNP: rs762151808
rs762151808
0.010 GeneticVariation BEFREE A rare S65C mutation and a novel A271S mutation were also found in this study; the latter patient had 4+ iron in the liver and later developed heart failure with cardiac iron. 20208481

2010

dbSNP: rs9909004
rs9909004
0.020 GeneticVariation BEFREE A recently discovered cardiac-specific regulatory variant for PRKCA (rs9909004) was independently associated with a decreased risk for all-cause mortality in patients with HF. 31728800

2019

dbSNP: rs397516089
rs397516089
0.010 GeneticVariation BEFREE A second pediatric patient presented with heart failure and was found to carry a de novo MYH7 R369Q mutation. 20031619

2009

dbSNP: rs5443
rs5443
0.020 GeneticVariation BEFREE A total of 350 subjects enrolled in the genetic substudy (GRAHF [Genetic Risk Assessment of Heart Failure in African Americans]) were genotyped for the C825T polymorphism. 25306451

2014

dbSNP: rs1429117513
rs1429117513
0.010 GeneticVariation BEFREE A total of 350 subjects enrolled in the genetic substudy (GRAHF [Genetic Risk Assessment of Heart Failure in African Americans]) were genotyped for the C825T polymorphism. 25306451

2014

dbSNP: rs1042713
rs1042713
0.040 GeneticVariation BEFREE ADRB2 polymorphism Arg16Gly modifies the natural outcome of heart failure and dictates therapeutic response to β-blockers in patients with heart failure. 30374408

2018

dbSNP: rs1258130495
rs1258130495
0.010 GeneticVariation BEFREE ADRB2 polymorphism Arg16Gly modifies the natural outcome of heart failure and dictates therapeutic response to β-blockers in patients with heart failure. 30374408

2018

dbSNP: rs671
rs671
0.020 GeneticVariation BEFREE ALDH2 rs671 polymorphism is proven to be closely related to the prevalence of CAD, hypertension, diabetes mellitus and alcoholism, which are etiological factors of heart failure. 27742538

2017

dbSNP: rs10501920
rs10501920
0.010 GeneticVariation BEFREE Also, rs10501920 in CNTN5 was associated with AF (p = 9.4 x 10(-6)) and HF (p = 1.2 x 10(-4)). 17903304

2007

dbSNP: rs2149954
rs2149954
0.010 GeneticVariation BEFREE Altogether, nominally significant associations between the rs2149954 minor allele and a decreased risk of heart attack and heart failure as well as increased physical functioning were found in the long-lived individuals. 28100865

2017

dbSNP: rs76992529
rs76992529
TTR
0.060 GeneticVariation BEFREE Among individuals of African or Hispanic/Latino ancestry enrolled in 2 academic medical center-based biobanks, the TTR V122I genetic variant was significantly associated with heart failure. 31821430

2019

dbSNP: rs1801253
rs1801253
0.100 GeneticVariation BEFREE An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study. 12921807

2003

dbSNP: rs699
rs699
AGT
0.040 GeneticVariation BEFREE Angiotensinogen M235T and T174M gene polymorphisms in combination doubles the risk of mortality in heart failure. 17145981

2007

dbSNP: rs10519210
rs10519210
0.800 GeneticVariation GWASCAT Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 20445134

2010

dbSNP: rs10519210
rs10519210
0.800 GeneticVariation GWASDB Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 20445134

2010

dbSNP: rs11172782
rs11172782
0.800 GeneticVariation GWASDB Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 20445134

2010

dbSNP: rs11172782
rs11172782
0.800 GeneticVariation GWASCAT Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 20445134

2010

dbSNP: rs1520832
rs1520832
0.800 GeneticVariation GWASCAT Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 20445134

2010