DisGeNET - a database of gene-disease associations

Hepatitis B, C0019163

Variant: rs9277542 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs9277542

HLA-DPB1

0.710

GeneticVariation

BEFREE

In addition, rs9277471 and rs9277542 variant genotypes significantly decreased the risk of HBV infection compared to healthy controls in an additive model of the Chinese Han population (OR=0.53, 95% CI=0.29-0.98, P=0.042; OR=0.53, 95% CI=0.29-0.97, P=0.039) and in a dominant model of the Chinese female population (OR=0.50, 95% CI=0.31-0.80, P=0.004; OR=0.49, 95% CI=0.31-0.79, P=0.003).

27291710

2016

dbSNP:

rs9277542

HLA-DPB1

0.710

GeneticVariation

GWASDB

A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.

23760081

2013

dbSNP:

rs9277542

HLA-DPB1

0.710

GeneticVariation

GWASDB

Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.

22737229

2012