rs41511344
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The S810L mutation within the human mineralocorticoid receptor (MR S810L) induces severe hypertension and switches progesterone from antagonist to agonist.
|
15908963 |
2005 |
rs41511344
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension.
|
15134816 |
2004 |
rs41511344
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.
|
12538613 |
2003 |
rs41511344
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We describe a mutation in the mineralocorticoid receptor (MR), S810L, that causes early-onset hypertension that is markedly exacerbated in pregnancy.
|
10884226 |
2000 |
rs41511344
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A missense mutation at codon 810 (Ser --> Leu) of the mineralocorticoid receptor was recently observed in a family with early manifestation of hypertension.
|
15117605 |
2004 |
rs41511344
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Here, we screened 942 Japanese patients with hypertension for the S810L mutation in exon 6 in the MR. We did not identify the S810L mutation in our hypertensive population, indicating that S810L does not play a major role in the etiology of essential hypertension in Japanese.
|
16419642 |
2005 |
rs5522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Genetic variation in <i>MR</i> (rs5522) and comorbidity with hypertension were significantly and potentially associated with prognosis when treated with ADT, respectively.
|
30619769 |
2018 |
rs5522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of this study was to analyze the association between the MR p.I180V polymorphism with hypertension and markers of cardiovascular risk.
|
19955850 |
2010 |
rs5522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
One haplotype, which included the G allele of the rs5522</span>, was also associated with reduced risk of HTN and four haplotypes which included the A allele were associated with increased risk of HTN.
|
19325532 |
2009 |
rs1040288
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results reveal a possible association between the rs11099680 RAAS polymorphism and uncontrolled AHT in MS-diagnosed patients. rs1040288 appears to be associated with uncontrolled blood pressure regardless of MS profile.
|
21471972 |
2011 |
rs10519963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs (rs11737660, rs6810951, and rs10519963) in NR3C2 correlate with both blood pressure and hypertension.
|
21342026 |
2011 |
rs11099680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results reveal a possible association between the rs11099680 RAAS polymorphism and uncontrolled AHT</span> in MS-diagnosed patients. rs1040288 appears to be associated with uncontrolled blood pressure regardless of MS profile.
|
21471972 |
2011 |
rs13306592
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequencies of the F826Y mutation in the hypertensive population (3/942) and in the hypertensive group (5/ 1,480) and the normotensive group (8/2,175) in the general population were not significantly different, suggesting that this mutation does not greatly affect hypertension.
|
16419642 |
2005 |
rs6810951
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs (rs11737660, rs6810951, and rs10519963) in NR3C2 correlate with both blood pressure and hypertension.
|
21342026 |
2011 |