|
rs11038357
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs118039499
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs12138950
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs17477923
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs2046045
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs2983514
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs66760320
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs8077245
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs925488
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
|
30367059 |
2018 |
|
rs28937584
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant Mice.
|
30132406 |
2018 |
|
rs3789604
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The C allele of rs3789604 (PTPN22) was a significant risk factor for LD-associated hyperthyroidism in GD patients, whereas C allele of GPR174 rs3827440 and G allele of RNASET2 rs9355610 appeared to be a protective factor for this disease.
|
28568286 |
2018 |
|
rs3827440
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results from logistic regression indicted that among the GD patients, C carriers of PTPN22 rs3789604 were associated with a higher risk of LD-associated hyperthyroidism, while C carriers of rs3827440 (GPR174) and G carriers of rs9355610 (RNASET2) were associated with a reduced risk of LD-associated hyperthyroidism.
|
28568286 |
2018 |
|
rs9355610
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The C allele of rs3789604 (PTPN22) was a significant risk factor for LD-associated hyperthyroidism in GD patients, whereas C allele of GPR174 rs3827440 and G allele of RNASET2 rs9355610 appeared to be a protective factor for this disease.
|
28568286 |
2018 |
|
rs1311839715
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel KCNJ18 mutation, G169R, was first reported to be associated with hypokalemic periodic paralysis without hyperthyroidism.
|
27178871 |
2016 |
|
rs1991517
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although no significant difference was found in TSHR D727E polymorphism frequencies between the patients with nodular goiters (26/123 patients, 21.1%) and the controls (12/97 patients, 12.4%) (P = 0.107), the frequency of the TSHR D727E polymorphism in the hyperthyroid+subclinical hyperthyroid patient groups (23%) was significantly higher than in the control subjects (12.4%) (P = 0.024).
|
27525921 |
2016 |
|
rs4416670
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also showed that the T allele of rs4416670 polymorphism was associated with increased risk of hyperthyroidism in patients treated for six months, independently of their initial diagnosis.
|
26955881 |
2016 |
|
rs12722039
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of genotypes (HLA DRB1*03, DQA1*05, DQB1*02; CTLA4 49A/G, CT60 A/G; PTPN22 C/T) in relation to phenotypes (age, sex, severity (clinical, biochemical, and immunological)) of hyperthyroidism and environmental factors (smoking, stress questionnaires).
|
22968483 |
2012 |
|
rs17879469
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of genotypes (HLA DRB1*03, DQA1*05, DQB1*02; CTLA4 49A/G, CT60 A/G; PTPN22 C/T) in relation to phenotypes (age, sex, severity (clinical, biochemical, and immunological)) of hyperthyroidism and environmental factors (smoking, stress questionnaires).
|
22968483 |
2012 |
|
rs231775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of genotypes (HLA DRB1*03, DQA1*05, DQB1*02; CTLA4 49A/G, CT60 A/G; PTPN22 C/T) in relation to phenotypes (age, sex, severity (clinical, biochemical, and immunological)) of hyperthyroidism and environmental factors (smoking, stress questionnaires).
|
22968483 |
2012 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the results obtained no statistically significant difference was found in Pgp C3435T polymorphism between hypo- and hyperthyroidism patients.
|
17891478 |
2008 |
|
rs121908873
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is consistent with the finding that only the index patient with the additional somatic mutation S281N was hyperthyroid.
|
18466076 |
2008 |
|
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prevalences of hypothyroidism and hyperthyroidism are similar in C282Y homozygotes without previous hemochromatosis diagnoses and controls.
|
18651828 |
2008 |
|
rs121908879
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A naturally occurring mutation in the ectodomain of the TSH receptor (TSHr), K183R, has been described recently in a familial case of gestational hyperthyroidism.
|
11923469 |
2002 |
|
rs1482760341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We described a large family with a relatively not severe phenotype of ALS (due to a leu144phe SOD1 mutation) that was compromised in one patient by a concomitant hyperthyroidism.
|
11676987 |
2001 |
|
rs571893270
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein, we report the molecular characterization of a case of severe congenital hyperthyroidism with a history of hyperthyroidism in the paternal aunt and the paternal grandmother, who were both found to be heterozygous for a mutation (R528H) located in exon 10 of the TSHR gene.
|
9589634 |
1998 |