Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7850258
rs7850258
PTCSC2
0.820 GeneticVariation GWASDB Four single-nucleotide polymorphisms (SNPs) in linkage disequilibrium at 9q22 near FOXE1 were associated with hypothyroidism at genome-wide significance, the strongest being rs7850258 (odds ratio [OR] 0.74, p = 3.96 × 10(-9)). 21981779

2011
dbSNP: rs7850258
rs7850258
PTCSC2
0.820 GeneticVariation GWASCAT Four single-nucleotide polymorphisms (SNPs) in linkage disequilibrium at 9q22 near FOXE1 were associated with hypothyroidism at genome-wide significance, the strongest being rs7850258 (odds ratio [OR] 0.74, p = 3.96 × 10(-9)). 21981779

2011
dbSNP: rs7850258
rs7850258
PTCSC2
0.820 GeneticVariation BEFREE Four single-nucleotide polymorphisms (SNPs) in linkage disequilibrium at 9q22 near FOXE1 were associated with hypothyroidism at genome-wide significance, the strongest being rs7850258 (odds ratio [OR] 0.74, p = 3.96 × 10(-9)). 21981779

2011
dbSNP: rs7850258
rs7850258
PTCSC2
0.820 GeneticVariation GWASDB Novel associations for hypothyroidism include known autoimmune risk loci. 22493691

2012
dbSNP: rs7850258
rs7850258
PTCSC2
0.820 GeneticVariation BEFREE Quantitative reporter assays in oral epithelial and thyroid cell lines show that the rs7850258 allele (G) associated with CLP and hypothyroidism has significantly greater enhancer activity than the allele associated with thyroid cancer (A). 25652407

2015
dbSNP: rs7850258
rs7850258
PTCSC2
0.820 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs17020055
rs17020055
VAV3
0.800 GeneticVariation GWASDB Novel associations for hypothyroidism include known autoimmune risk loci. 22493691

2012
dbSNP: rs17020055
rs17020055
VAV3
0.800 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.800 GeneticVariation GWASDB Novel associations for hypothyroidism include known autoimmune risk loci. 22493691

2012
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.800 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.800 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs3184504
rs3184504
ATXN2 ; SH2B3
0.800 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs925489
rs925489
PTCSC2
0.800 GeneticVariation GWASDB Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. 21981779

2011
dbSNP: rs10759944
rs10759944
PTCSC2
0.710 GeneticVariation GWASDB Novel associations for hypothyroidism include known autoimmune risk loci. 22493691

2012
dbSNP: rs10759944
rs10759944
PTCSC2
0.710 GeneticVariation GWASDB Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. 21981779

2011
dbSNP: rs10759944
rs10759944
PTCSC2
0.710 GeneticVariation BEFREE FOXE1 variants, associated with hypothyroidism, were not genome-wide significant (rs10759944: p = 1.08×10-6, β = -0.05). 25436638

2014
dbSNP: rs10036386
rs10036386
PDE8B
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs10180754
rs10180754
LINC01934
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs10223666
rs10223666
LOC105375069 ; LOC107986598
0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs10277273
rs10277273
FOXK1
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs1032129
rs1032129
TNFRSF11B
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs10424978
rs10424978 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs1047578
rs1047578
NAA25
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs10489626
rs10489626
IL12RB2
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs1050976
rs1050976
IRF4
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019