|
rs1463038513
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings suggest that the I1307K sequence is relatively rare in the germline of Jewish as well as non-Jewish IBD patients.
|
10445854 |
1999 |
|
rs1801155
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings suggest that the I1307K sequence is relatively rare in the germline of Jewish as well as non-Jewish IBD patients.
|
10445854 |
1999 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
There is an association between the thermolabile MTHFR C677T variant and IBD.
|
10446107 |
1999 |
|
rs1463038513
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Prevalence of the I1307K variant was not significantly different among individuals with IBD, Crohn's disease, ulcerative colitis, and unaffected relatives (6.9%, 7.6%, 4.7%, and 6.2%, respectively), and the mutation was detected in only one of five IBD-affected individuals with a diagnosis of CRC.
|
11354631 |
2001 |
|
rs1801155
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Prevalence of the I1307K variant was not significantly different among individuals with IBD, Crohn's disease, ulcerative colitis, and unaffected relatives (6.9%, 7.6%, 4.7%, and 6.2%, respectively), and the mutation was detected in only one of five IBD-affected individuals with a diagnosis of CRC.
|
11354631 |
2001 |
|
rs1801275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not find any significant correlation between a 32-bp deletion variant of CCR5 or a single nucleotide change A1902G (Gln576Arg) of IL4RA, and IBD phenotypes, with the exception that in the UC group homozygosity for the G1902 allele of IL4RA was less frequent (0.019 vs 0.049, P=0.038).
|
11378820 |
2001 |
|
rs751377893
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Neither of the allele frequencies of genetic determinants for thrombophilia (coagulation factor V 1691G-->A (factor V Leiden) and factor II 20210G-->A polymorphisms) in the background population differed significantly from that in IBD patients.
|
11843038 |
2002 |
|
rs1183194405
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found no evidence of association of factor XIII valine34leucine polymorphism and inflammatory bowel disease.
|
11953689 |
2002 |
|
rs2066844
|
|
|
0.790 |
GeneticVariation |
BEFREE |
A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls.
|
12115195 |
2002 |
|
rs2066845
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls.
|
12115195 |
2002 |
|
rs2066842
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls.
|
12115195 |
2002 |
|
rs2066844
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Two cohorts of consecutively identified patients referred to an inflammatory bowel disease center (n = 142 collected between 1993 and 1996; n = 59 collected between 1999 and 2001) were genotyped for 3 single nucleotide variants of NOD2-R675W, G881R, and 3020insC-and phenotyped for disease behavior, disease location, and serum immune markers.
|
12198692 |
2002 |
|
rs2066845
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two cohorts of consecutively identified patients referred to an inflammatory bowel disease center (n = 142 collected between 1993 and 1996; n = 59 collected between 1999 and 2001) were genotyped for 3 single nucleotide variants of NOD2-R675W, G881R, and 3020insC-and phenotyped for disease behavior, disease location, and serum immune markers.
|
12198692 |
2002 |
|
rs751377893
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease.
|
12454577 |
2002 |
|
rs1188383936
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease.
|
12454577 |
2002 |
|
rs899127658
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease.
|
12454577 |
2002 |
|
rs5498
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in a Japanese population.
|
12477764 |
2003 |
|
rs2066844
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Our aim was to evaluate the allele frequencies of the CARD15 variants R702W, G908R, and 1007fs in Finnish inflammatory bowel disease (IBD) patients and to search for possible associations between CARD15 variants and occurrence of familial forms of IBD or complicated forms of CD.
|
12631669 |
2003 |
|
rs2066845
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our aim was to evaluate the allele frequencies of the CARD15 variants R702W, G908R, and 1007fs in Finnish inflammatory bowel disease (IBD) patients and to search for possible associations between CARD15 variants and occurrence of familial forms of IBD or complicated forms of CD.
|
12631669 |
2003 |
|
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Significant association of Ala893 with IBD was observed by both case-control analysis (P=.002) and the pedigree disequilibrium test (PDT [P=.00020-.00030]) but not for the Asn21Asp or C3435T polymorphisms.
|
14610718 |
2003 |
|
rs9282564
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant association of Ala893 with IBD was observed by both case-control analysis (P=.002) and the pedigree disequilibrium test (PDT [P=.00020-.00030]) but not for the Asn21Asp or C3435T polymorphisms.
|
14610718 |
2003 |
|
rs4986790
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A TDT on 318 IBD trios demonstrated preferential transmission of the TLR4 Asp299Gly polymorphism from heterozygous parents to affected children (T/U: 68/34, p = 0.01).
|
15194649 |
2004 |
|
rs771184127
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A TDT on 318 IBD trios demonstrated preferential transmission of the TLR4 Asp299Gly polymorphism from heterozygous parents to affected children (T/U: 68/34, p = 0.01).
|
15194649 |
2004 |
|
rs11554495
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our data indicate that both keratin 8 mutations, G62C and Y54H, do not play a relevant pathogenic role in inflammatory bowel disease.
|
15248378 |
2004 |
|
rs57749775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data indicate that both keratin 8 mutations, G62C and Y54H, do not play a relevant pathogenic role in inflammatory bowel disease.
|
15248378 |
2004 |