|
rs57749775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data indicate that both keratin 8 mutations, G62C and Y54H, do not play a relevant pathogenic role in inflammatory bowel disease.
|
15248378 |
2004 |
|
rs2066844
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Analysis of the three common mutations in the CARD15 gene (R702W, G908R and 1007fs) in South African colored patients with inflammatory bowel disease.
|
15967635 |
2005 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We present here a study of the genetic variation described in that report in two well-powered, independent case-control cohorts and one family-based collection, and confirm the proposed association between IBD and the R30Q variant of DLG5 in two of the three studies.
|
15841097 |
2005 |
|
rs2066845
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Analysis of the three common mutations in the CARD15 gene (R702W, G908R and 1007fs) in South African colored patients with inflammatory bowel disease.
|
15967635 |
2005 |
|
rs4986791
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The Asp299Gly and Thr399Ile variants do not show an association with CD, UC, or IBD as a group, indicating that these polymorphisms are likely not the causal ones.
|
15905704 |
2005 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.
|
16262529 |
2005 |
|
rs2476601
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These results indicate that the PTPN22 1858C-->T polymorphism does not appear to play a major role in IBD predisposition in our population.
|
16185327 |
2005 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.
|
16262529 |
2005 |
|
rs11209026
|
|
A |
0.900 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
|
17068223 |
2006 |
|
rs2076756
|
|
|
0.820 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
|
17068223 |
2006 |
|
rs2076756
|
|
|
0.820 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
|
17068223 |
2006 |
|
rs7517847
|
|
C |
0.720 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
|
17068223 |
2006 |
|
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A meta-analysis was carried out of our results and those from 8 previously published association studies of the C3435T variant in inflammatory bowel disease.
|
16633048 |
2006 |
|
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study we have undertaken a meta-analysis of the available findings obtained with two SNPs polymorphism (C3435T and G2677T/A) in IBD; a significant association of 3435T allele and 3435TT genotype has been found with UC (OR = 1.17, P = 0.003 and OR = 1.36, P = 0.017, respectively).
|
16773678 |
2006 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We assess the frequency of the CARD15 SNPs and of the R30Q mutation in DLG5 and their contribution to the development of CD in a cohort of unrelated IBD patients (151 CD, 325 ulcerative colitis (UC)) and healthy controls (236) from South-east Norway (IBSEN cohort).
|
16493449 |
2006 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The frequency of the R30Q variant allele was not significantly different in IBD (22.0%), CD (20.8%), and UC (27.6%) patients compared with healthy control subjects (28.0%).
|
16670524 |
2006 |
|
rs2066845
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To investigate the distribution of CARD15/NOD2 (Arg702Trp, Gly908Arg and Leu1007fsinsC) and TLR4 (Asp299Gly) polymorphisms in Chilean patients with IBD.Methods.
|
16840031 |
2006 |
|
rs4986790
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To investigate the distribution of CARD15/NOD2 (Arg702Trp, Gly908Arg and Leu1007fsinsC) and TLR4 (Asp299Gly) polymorphisms in Chilean patients with IBD.Methods.
|
16840031 |
2006 |
|
rs5498
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In the second approach, we typed four nonsynonymous polymorphisms in genes C3 (R102G and L314P) and ICAM1 (G241R and K469E) in four independent cohorts totaling 2178 IBD cases.
|
16570073 |
2006 |
|
rs5498
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate polymorphisms in the NOD2/CARD15 (R702W, G908R, and 3020insC), NOD1/CARD4 (E266K, D372N), and ICAM-1 (G241R, K469E) genes, which are known to be associated with inflammation, in Turkish patients with inflammatory bowel disease and healthy control groups.
|
16741608 |
2006 |
|
rs771184127
|
|
|
0.060 |
GeneticVariation |
BEFREE |
To investigate the distribution of CARD15/NOD2 (Arg702Trp, Gly908Arg and Leu1007fsinsC) and TLR4 (Asp299Gly) polymorphisms in Chilean patients with IBD.Methods.
|
16840031 |
2006 |
|
rs771184127
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This is underscored by the finding of the association between CARD15 variants and Crohn's disease (CD) and D299G in Toll-like receptor (TLR) 4 and IBD.
|
16374251 |
2006 |
|
rs1050152
|
|
|
0.040 |
GeneticVariation |
BEFREE |
To determine whether the TC haplotype is also associated with IBD in a Japanese population, we genotyped L503F and -207G/C variants in Japanese subjects.
|
16373276 |
2006 |
|
rs2032582
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In this study we have undertaken a meta-analysis of the available findings obtained with two SNPs polymorphism (C3435T and G2677T/A) in IBD; a significant association of 3435T allele and 3435TT genotype has been found with UC (OR = 1.17, P = 0.003 and OR = 1.36, P = 0.017, respectively).
|
16773678 |
2006 |
|
rs1545620
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Common variation in MYO9B was associated with susceptibility to inflammatory bowel disease in all 3 cohorts examined (most associated SNP, rs1545620; meta-analysis P = 1.9 x 10(-6); odds ratio, 1.2), with the same alleles showing association as reported for celiac disease.
|
17087940 |
2006 |