Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE We carried out a case-control study to examine the association of MDR1 (C1236T and C3435T), GSTT1, and GSTM1 polymorphisms with the risk of IBD. 26604430

2015

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE The statistically significant correlation was discovered between gender and C3435T</span> genotype both for IBD and CD patients, with 3435CT heterozygote prevailing in IBD and CD males. 25712653

2015

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE This meta-analysis indicated that the C3435T polymorphism of MDR1 may not confer susceptibility to IBD. 24449364

2014

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE Effect of the C3435T polymorphism of the multidrug resistance 1 gene on the severity of inflammatory bowel disease in Iranian Azeri Turks. 23828747

2014

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE The C3435T polymorphism of the ABCB1/MDR1 gene is not a risk factor for IBD, including UC and CD, in the population coming from central Poland. 22661185

2012

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE The role of the single nucleotide polymorphisms (SNPs) on positions 2677G>T/A and 3435C>T of the multi-drug-resistance gene 1 (MDR1) in inflammatory bowel disease (IBD) remains unclear. 17665184

2007

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE Interestingly, a negative association was found between MDR1 C3435T polymorphism in patients with a positive family history for IBD (OR = 0.44; 95% CI: 0.20-0.95) and articular manifestations (OR = 0.29; 95% CI: 0.13-0.68). 17260353

2007

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE A meta-analysis was carried out of our results and those from 8 previously published association studies of the C3435T variant in inflammatory bowel disease. 16633048

2006

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE In this study we have undertaken a meta-analysis of the available findings obtained with two SNPs polymorphism (C3435T and G2677T/A) in IBD; a significant association of 3435T allele and 3435TT genotype has been found with UC (OR = 1.17, P = 0.003 and OR = 1.36, P = 0.017, respectively). 16773678

2006

dbSNP: rs1045642
rs1045642
0.100 GeneticVariation BEFREE Significant association of Ala893 with IBD was observed by both case-control analysis (P=.002) and the pedigree disequilibrium test (PDT [P=.00020-.00030]) but not for the Asn21Asp or C3435T polymorphisms. 14610718

2003