|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis of associations between DLG5 R30Q and P1371Q polymorphisms and susceptibility to inflammatory bowel disease.
|
27633114 |
2016 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our study does not support the effect of the R30Q DLG5 variant in CeD or IBD predisposition in the Spanish population.
|
20796250 |
2011 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A significant epistatic interaction between P1371Q and R30Q was observed, suggesting that P1371Q is complementary to R30Q, with R30Q exhibiting a dominant effect in IBD susceptibility.
|
22065243 |
2011 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men.
|
20037206 |
2009 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The R30Q variant in the DLG5 gene does not appear to be associated with an overall increase in the risk of disease in a British IBD cohort, but differences in its frequency in subgroups of CD patients warrant further investigation.
|
16944184 |
2007 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A significant association between the DLG5 variant (R3</span>0Q) and inflammatory bowel disease (IBD) has been confirmed in several independent adult IBD cohorts.
|
17156146 |
2007 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis demonstrates that the minor allele of R30Q is not a risk factor for IBD across populations.
|
17455201 |
2007 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We assess the frequency of the CARD15 SNPs and of the R30Q mutation in DLG5 and their contribution to the development of CD in a cohort of unrelated IBD patients (151 CD, 325 ulcerative colitis (UC)) and healthy controls (236) from South-east Norway (IBSEN cohort).
|
16493449 |
2006 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The frequency of the R30Q variant allele was not significantly different in IBD (22.0%), CD (20.8%), and UC (27.6%) patients compared with healthy control subjects (28.0%).
|
16670524 |
2006 |
|
rs1248696
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We present here a study of the genetic variation described in that report in two well-powered, independent case-control cohorts and one family-based collection, and confirm the proposed association between IBD and the R30Q variant of DLG5 in two of the three studies.
|
15841097 |
2005 |