Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs771184127
rs771184127
0.060 GeneticVariation BEFREE The TLR4-Thr399Ile variant was strongly associated with susceptibility to IBD, whereas TLR4-Asp299Gly seems to play a role in the clinical expression of UC. 29055077

2017

dbSNP: rs771184127
rs771184127
0.060 GeneticVariation BEFREE No association of IBD with the TLR4 SNPs was found in either cohort (allele frequencies: D299G-controls 3.9%, CD 3.7%, UC 3.4%, P > 0.05; T399I-controls 2.9%, CD 3.0%, UC 3.4%, P > 0.05). 18680223

2008

dbSNP: rs771184127
rs771184127
0.060 GeneticVariation BEFREE The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease. 18174680

2007

dbSNP: rs771184127
rs771184127
0.060 GeneticVariation BEFREE To investigate the distribution of CARD15/NOD2 (Arg702Trp, Gly908Arg and Leu1007fsinsC) and TLR4 (Asp299Gly) polymorphisms in Chilean patients with IBD.Methods. 16840031

2006

dbSNP: rs771184127
rs771184127
0.060 GeneticVariation BEFREE This is underscored by the finding of the association between CARD15 variants and Crohn's disease (CD) and D299G in Toll-like receptor (TLR) 4 and IBD. 16374251

2006

dbSNP: rs771184127
rs771184127
0.060 GeneticVariation BEFREE A TDT on 318 IBD trios demonstrated preferential transmission of the TLR4 Asp299Gly polymorphism from heterozygous parents to affected children (T/U: 68/34, p = 0.01). 15194649

2004