|
rs34481144
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found evidence of a new association of rs34481144 with severe influenza in three influenza-infected cohorts characterized by different levels of influenza illness severity.
|
28714988 |
2017 |
|
rs1048479
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a second phase of the study, the rs113350588 and rs1048479 polymorphisms identified in this sample were genotyped in a sample of 356 subjects from the northern and northeastern regions of Brazil with a diagnosis of pandemic influenza.
|
26436774 |
2015 |
|
rs113350588
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a second phase of the study, the rs113350588 and rs1048479 polymorphisms identified in this sample were genotyped in a sample of 356 subjects from the northern and northeastern regions of Brazil with a diagnosis of pandemic influenza.
|
26436774 |
2015 |
|
rs8099917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we demonstrate that the presence of the IL-28B TG/GG genotype (rs8099917, minor-allele) was associated with increased seroconversion following influenza vaccination (OR 1.99 p = 0.038).
|
25503988 |
2014 |
|
rs1468575151
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found a novel mutation, N84S in the PB1F2 protein of 9·35% of the highly pathogenic avian influenza H5N1 influenza viruses.
|
22788742 |
2013 |
|
rs7744020
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variants in the Human Leukocyte Antigen (HLA)- DQ region were associated with age of onset (rs7744020 P = 7.9×10(-9) beta -1.9 years) and varied significantly among cases with onset after the 2009 H1N1 influenza pandemic compared to previous years (rs9271117 P = 7.8 × 10(-10) OR 0.57).
|
24204295 |
2013 |
|
rs9271117
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variants in the Human Leukocyte Antigen (HLA)- DQ region were associated with age of onset (rs7744020 P = 7.9×10(-9) beta -1.9 years) and varied significantly among cases with onset after the 2009 H1N1 influenza pandemic compared to previous years (rs9271117 P = 7.8 × 10(-10) OR 0.57).
|
24204295 |
2013 |
|
rs2229291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Recent studies suggested that the thermolabile phenotype of carnitine palmitoyltransferase II (CPT II) variation [F352C] was closely related to the pathomechanism of influenza-associated encephalopathy (IAE) in Japanese, causing mitochondrial ATP utilization failure during periods of high fever, resulting in brain edema.
|
21277129 |
2012 |
|
rs773340854
|
|
|
0.010 |
GeneticVariation |
BEFREE |
On the contrary, the presence of the TLR4-T399I polymorphism was associated with a 2-fold decreased risk of Haemophilus influenzae carriage (OR = 0.38, 95% CI = 0.15 to 0.96, P = 0.038).
|
21159925 |
2011 |
|
rs1801274
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The functional single nucleotide polymorphism rs1801274 in the FCGR2A gene (His131Arg) influences the efficiency of hIgG2 binding, the main isotype produced in response to encapsulated bacteria like Streptococcus pneumoniae and Haemophilus influenzae.
|
16893392 |
2006 |