rs2229291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Recent studies suggested that the thermolabile phenotype of carnitine palmitoyltransferase II (CPT II) variation [F352C] was closely related to the pathomechanism of influenza-associated encephalopathy (IAE) in Japanese, causing mitochondrial ATP utilization failure during periods of high fever, resulting in brain edema.
|
21277129 |
2012 |
rs2275913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequencies of the IL-1β rs16944 (P = 0.007) and IL-17 rs2275913 (P = 0.006) genotypes were associated with severe influenza disease, while the frequencies of IL-10 rs1800872 and IL-28 rs8099917 were not associated with the disease (P > 0.05).
|
31196204 |
2019 |
rs2476601
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no significant difference among healthy pregnant R620W carriers and non-carriers in H1N1 antibody seroconversion rates after influenza vaccination.
|
28723925 |
2017 |
rs34481144
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found evidence of a new association of rs34481144 with severe influenza in three influenza-infected cohorts characterized by different levels of influenza illness severity.
|
28714988 |
2017 |
rs763362
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Comparison between 145 patients hospitalized with severe influenza at intensive care units (ICU) with 139 matched influenza-positive outpatients showed that presence of the rs763362 G allele (GG, AG) was associated with occurrence of severe influenza infections (P = .0076).
|
31114873 |
2019 |
rs773340854
|
|
|
0.010 |
GeneticVariation |
BEFREE |
On the contrary, the presence of the TLR4-T399I polymorphism was associated with a 2-fold decreased risk of Haemophilus influenzae carriage (OR = 0.38, 95% CI = 0.15 to 0.96, P = 0.038).
|
21159925 |
2011 |
rs7744020
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variants in the Human Leukocyte Antigen (HLA)- DQ region were associated with age of onset (rs7744020 P = 7.9×10(-9) beta -1.9 years) and varied significantly among cases with onset after the 2009 H1N1 influenza pandemic compared to previous years (rs9271117 P = 7.8 × 10(-10) OR 0.57).
|
24204295 |
2013 |
rs8072510
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Neither rs12252 nor rs8072510 showed an association according to the presence of clinical risk factors for influenza complications (P > 0.05), suggesting that these factors did not modify associations between the SNPs and hospitalized influenza.
|
29053189 |
2018 |
rs8099917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we demonstrate that the presence of the IL-28B TG/GG genotype (rs8099917, minor-allele) was associated with increased seroconversion following influenza vaccination (OR 1.99 p = 0.038).
|
25503988 |
2014 |
rs9271117
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variants in the Human Leukocyte Antigen (HLA)- DQ region were associated with age of onset (rs7744020 P = 7.9×10(-9) beta -1.9 years) and varied significantly among cases with onset after the 2009 H1N1 influenza pandemic compared to previous years (rs9271117 P = 7.8 × 10(-10) OR 0.57).
|
24204295 |
2013 |