Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs34481144
rs34481144
0.010 GeneticVariation BEFREE We found evidence of a new association of rs34481144 with severe influenza in three influenza-infected cohorts characterized by different levels of influenza illness severity. 28714988

2017

dbSNP: rs2275913
rs2275913
0.010 GeneticVariation BEFREE The frequencies of the IL-1β rs16944 (P = 0.007) and IL-17 rs2275913 (P = 0.006) genotypes were associated with severe influenza disease, while the frequencies of IL-10 rs1800872 and IL-28 rs8099917 were not associated with the disease (P > 0.05). 31196204

2019

dbSNP: rs16944
rs16944
0.010 GeneticVariation BEFREE The frequencies of the IL-1β rs16944 (P = 0.007) and IL-17 rs2275913 (P = 0.006) genotypes were associated with severe influenza disease, while the frequencies of IL-10 rs1800872 and IL-28 rs8099917 were not associated with the disease (P > 0.05). 31196204

2019

dbSNP: rs1468575151
rs1468575151
0.010 GeneticVariation BEFREE We found a novel mutation, N84S in the PB1F2 protein of 9·35% of the highly pathogenic avian influenza H5N1 influenza viruses. 22788742

2013

dbSNP: rs2476601
rs2476601
0.010 GeneticVariation BEFREE There was no significant difference among healthy pregnant R620W carriers and non-carriers in H1N1 antibody seroconversion rates after influenza vaccination. 28723925

2017

dbSNP: rs8072510
rs8072510
0.010 GeneticVariation BEFREE Neither rs12252 nor rs8072510 showed an association according to the presence of clinical risk factors for influenza complications (P > 0.05), suggesting that these factors did not modify associations between the SNPs and hospitalized influenza. 29053189

2018

dbSNP: rs1048479
rs1048479
0.010 GeneticVariation BEFREE In a second phase of the study, the rs113350588 and rs1048479 polymorphisms identified in this sample were genotyped in a sample of 356 subjects from the northern and northeastern regions of Brazil with a diagnosis of pandemic influenza. 26436774

2015

dbSNP: rs113350588
rs113350588
0.010 GeneticVariation BEFREE In a second phase of the study, the rs113350588 and rs1048479 polymorphisms identified in this sample were genotyped in a sample of 356 subjects from the northern and northeastern regions of Brazil with a diagnosis of pandemic influenza. 26436774

2015

dbSNP: rs4986791
rs4986791
0.020 GeneticVariation BEFREE On the contrary, the presence of the TLR4-T399I polymorphism was associated with a 2-fold decreased risk of Haemophilus influenzae carriage (OR = 0.38, 95% CI = 0.15 to 0.96, P = 0.038). 21159925

2011

dbSNP: rs4986791
rs4986791
0.020 GeneticVariation BEFREE TLR4 1196 C>T effects were similar to TLR4 896 A>G for brucellosis, cutaneous leishmaniasis, leprosy, typhoid fever and S. pyogenes tonsillar disease, and was protective for bacterial vaginosis in pregnancy (0.55; 95%CI 0.31-0.98) and Haemophilus influenzae tonsillar disease (0.42; 95%CI 0.17-1.00). 24282567

2013