|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Genetic variants of ACE (Insertion/Deletion) and AGT (M268T) genes in patients with diabetes and nephropathy.
|
24737640 |
2014 |
|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
To assess the antiproteinuric response to multifactorial treatment based on high doses of angiotensin II receptor antagonists (ARBs) (olmesartan) in patients with non-diabetic proteinuric nephropathies, according to three renin-angiotensin system (RAS) polymorphisms: insertion/deletion of the angiotensin converting enzyme (ACE) gene, the angiotensinogen gene M235T and the angiotensin II type 1 receptor (AT1R) A1166C.
|
24241364 |
2013 |
|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The frequency of T allele, MT/TT genotypes (AGT: M235T), and C allele 1166CC genotype (AGTR1: A1166C) was higher and associated with increased risk of DNP (235T, p < 0.0001; 235TT/MT, p < 0.01; 1166C, p < 0.007; 1166CC, p < 0.0001).
|
19108684 |
2009 |
|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
There were no differences in the frequencies of the AGT M235T and ACE I/D genotypes between Turkish patients with type 2 DM with and without nephropathy.
|
18413162 |
2008 |
|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Three SNPs within the AGT, including M235T and one SNP in the AGTR1, were also significantly associated with nephropathy (M235T P=0.01, odds ratio =0.74, 95% CI 0.59-0.94).
|
17143591 |
2007 |
|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The allele frequencies of AGT point mutation at 235 (M235T) was significantly higher in DM nephropathy but the genotypic frequencies were not.
|
12728975 |
2003 |
|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The ACE-I/D polymorphism was shown to be a risk factor of progression of renal disease and the AGT-M235T polymorphism was associated with the severity of arterial hypertension.
|
14610337 |
2003 |
|
rs1267969615
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In this meta-analysis, we attempted to derive pooled estimates for the putative associations between various cardiovascular-renal disorders and the M235T polymorphism of the angiotensinogen gene.
|
10100088 |
1999 |