Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs904520404
rs904520404
0.010 GeneticVariation BEFREE This condition is a renal-hepatic ciliopathy with phenotypic characteristics that include hepatosplenomegaly, hepatic fibrosis with bile cholestasis, increased kidney echogenicity, and end-stage renal disease.Here, we report a 13-year-old African-Caribbean female with areas of absence of heterozygosity suggesting parental consanguinity or identity by decent due to the founder effect, harboring a novel homozygous pathogenic variant (c.383C>G, p.S128*) in exon 3 of DCDC2. 31821705

2020

dbSNP: rs12513649
rs12513649
0.010 GeneticVariation BEFREE CREBRF rs12513649 and rs373863828 were genotyped in 2022 participants in a community-based cross-sectional study designed to identify determinants of diabetes and end-stage renal disease (ESRD). 31280340

2019

dbSNP: rs1801239
rs1801239
0.010 GeneticVariation BEFREE The CUBN CC or C-risk-allele of rs1801239 was associated with ESRD (OR 2.04 [1.07-3.87], p = 0.03) and peripheral artery disease (OR 2.08 [1.12-3.88], p = 0.021). 30557881

2019

dbSNP: rs373863828
rs373863828
0.010 GeneticVariation BEFREE CREBRF rs12513649 and rs373863828 were genotyped in 2022 participants in a community-based cross-sectional study designed to identify determinants of diabetes and end-stage renal disease (ESRD). 31280340

2019

dbSNP: rs373971520
rs373971520
0.010 GeneticVariation BEFREE A second variant at GNG7 (rs373971520; P = 2.17 × 10<sup>-8</sup>, OR = 1.46) remained associated with all-cause ESKD in the APOL1-negative analysis. 31092297

2019

dbSNP: rs77113398
rs77113398
0.010 GeneticVariation BEFREE Following extension analyses in 1910 non-diabetic ESKD cases and 908 non-diabetic non-nephropathy controls, a meta-analysis of 5342 AA all-cause ESKD cases and 6977 AA non-diabetic non-nephropathy controls revealed an additional novel all-cause ESKD locus at EFNB2 (rs77113398; P = 9.84 × 10<sup>-9</sup>; OR = 1.94). 31092297

2019

dbSNP: rs926632
rs926632
0.010 GeneticVariation BEFREE The minor allele of rs260741, rs197173, and rs926632 in EDN3 were associated with reduced risk of hospitalized bacteremia events in ESRD patients. 31167651

2019

dbSNP: rs9395890
rs9395890
0.010 GeneticVariation BEFREE Our findings indicate that rs9395890 is associated with susceptibility to ESRD in Taiwan population. 31382928

2019

dbSNP: rs11089781
rs11089781
0.010 GeneticVariation BEFREE Stratifying by APOL1 risk genotype (recessive) and adjusting for African ancestry identified a significant additive association between rs11089781 and ESKD in each stratum and in a meta-analysis [meta-analysis P  =  0.0070; odds ratio (OR) = 1.29]; ORs were consistent across APOL1 risk strata. 28339911

2018

dbSNP: rs11643718
rs11643718
0.010 GeneticVariation BEFREE The SLC12A3-Arg913Gln variation may be associated with increased blood pressure and UAER and, therefore, could be used to predict the development and progression of DN-ESRD in Chinese T2DM patients undergoing hemodialysis. 28744814

2018

dbSNP: rs1544410
rs1544410
VDR
0.010 GeneticVariation BEFREE In subgroup analysis by ethnicity for VDR rs1544410 gene polymorphism, we found significant differences under dominant model (SMD: -0.18 [-0.32, -0.05], P < .01) and AA versus GG comparison (SMD: -0.29 [-0.52, -0.06], P < .01) in Asian patients with ESRD, while nominally significant results (P < .05) were observed for AG versus GG and AA versus GG comparisons in European individuals with ESRD. 29794776

2018

dbSNP: rs17173608
rs17173608
0.010 GeneticVariation BEFREE We found that the G allele of chemerin rs17173608 compared to T allele decreased the risk of ESRD, and there was a significant association between chemerin and vaspin variants with plasma MDA level in a sample of the Iranian population. 29644922

2018

dbSNP: rs1801725
rs1801725
0.010 GeneticVariation BEFREE We conducted meta-analyses for calcium-sensing receptor gene (CaSR) rs1801725 polymorphism in patients with primary hyperparathyroidism and vitamin D receptor gene (VDR) rs1544410 polymorphism in patients with end-stage renal disease (ESRD). 29794776

2018

dbSNP: rs2236242
rs2236242
0.010 GeneticVariation BEFREE Chemerin rs17173608 and vaspin rs2236242 gene variants on the risk of end stage renal disease (ESRD) and correlation with plasma malondialdehyde (MDA) level. 29644922

2018

dbSNP: rs267607183
rs267607183
0.010 GeneticVariation BEFREE The second mutation (p.Arg218Gln) was found in two brothers with ESRD of unknown etiology. 30126379

2018

dbSNP: rs28935197
rs28935197
0.010 GeneticVariation BEFREE An atypical p.N215S variant of Fabry disease with end-stage renal failure. 30023289

2018

dbSNP: rs75444904
rs75444904
0.010 GeneticVariation BEFREE In an additional validation-cohort of EA (410 end-stage renal disease (ESRD) cases and 1308 controls), rs75444904 was associated with ESRD (OR = 1.22, P = 0.036). 29572449

2018

dbSNP: rs7708392
rs7708392
0.010 GeneticVariation BEFREE TNIP1 SNP (rs7708392) might be used to identify patients at risk of developing LN, which could help in early detection and treatment before progression to end-stage renal disease, improving patients' outcome and quality of life. 29589214

2018

dbSNP: rs11864909
rs11864909
0.010 GeneticVariation BEFREE The aim of this study was to investigate associations between two common single nucleotide polymorphisms - rs12917707 and rs11864909, located in the region of UMOD and chronic renal disease. 28954491

2017

dbSNP: rs183962941
rs183962941
0.010 GeneticVariation BEFREE One SNP (rs183962941), located in a non-coding region of UMOD, was nominally associated with ESRD (p = 0.008). 28609449

2017

dbSNP: rs4714384
rs4714384
0.010 GeneticVariation BEFREE EDN1 rs4714384 is very likely an important biomarker of CV events in ESRD patients. 28882114

2017

dbSNP: rs74315342
rs74315342
0.010 GeneticVariation BEFREE The most common podocin mutation, R138Q, is associated with early disease onset and rapid progression to end-stage renal disease. 29049388

2017

dbSNP: rs1049255
rs1049255
0.010 GeneticVariation BEFREE Our results suggested that rs1049255 polymorphism of CYBA modified the risk of ESRD (p  =  0.019; OR  =  0.625; 95%CI  =  0.424-0.921). 26627442

2016

dbSNP: rs10951982
rs10951982
0.010 GeneticVariation BEFREE The other three SNPs (rs10951982, rs6954996, and rs9374), in all comparison models, were not associated with ESRD risk (P > 0.05). 26841219

2016

dbSNP: rs13333226
rs13333226
0.010 GeneticVariation BEFREE A common variation rs13333226 in the promoter region of UMOD gene was independently associated with ESRD in Han Chinese. 27938332

2016