rs104894421
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs121434629
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs121913250
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs61753793
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs6413463
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs947141826
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Up-regulation of small GTP-binding proteins smg P21A and ras P21S during TPA-induced differentiation of human leukemia cell lines.
|
8429689 |
1993 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In contrast, associations for A1298C homozygotes (CC; OR = 0.26 with a 95% CI of 0.07--0.81) and C677T homozygotes (TT; OR = 0.49 with a 95% CI of 0.20--1.17) were observed for hyperdiploid leukemias (n = 138).
|
11274424 |
2001 |
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In contrast, associations for A1298C homozygotes (CC; OR = 0.26 with a 95% CI of 0.07--0.81) and C677T homozygotes (TT; OR = 0.49 with a 95% CI of 0.20--1.17) were observed for hyperdiploid leukemias (n = 138).
|
11274424 |
2001 |
rs1051266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In genomic DNAs prepared from 105 leukemia (n = 54) and non-leukemia (n = 51) specimens, PCR amplifications and direct sequencing of exon 3 identified a high-frequency G to A single nucleotide polymorphism at position 80 that resulted in a change of arginine-27 to histidine-27.
|
11705857 |
2001 |
rs1258094111
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The allelic frequencies of G/A80 were nearly identical for the non-leukemia (42.2% CGC and 57.8% CAC) and leukemia (40.7% CGC and 59.3% CAC) genomic DNAs.
|
11705857 |
2001 |
rs765669662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In genomic DNAs prepared from 105 leukemia (n = 54) and non-leukemia (n = 51) specimens, PCR amplifications and direct sequencing of exon 3 identified a high-frequency G to A single nucleotide polymorphism at position 80 that resulted in a change of arginine-27 to histidine-27.
|
11705857 |
2001 |
rs765669662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The allelic frequencies of G/A80 were nearly identical for the non-leukemia (42.2% CGC and 57.8% CAC) and leukemia (40.7% CGC and 59.3% CAC) genomic DNAs.
|
11705857 |
2001 |
rs775144154
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The allelic frequencies of G/A80 were nearly identical for the non-leukemia (42.2% CGC and 57.8% CAC) and leukemia (40.7% CGC and 59.3% CAC) genomic DNAs.
|
11705857 |
2001 |
rs1800562
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Its male-specificity, occurrence in childhood and the lack of a gene-dosage effect suggest that the C282Y association in childhood ALL may reflect the involvement of another HLA-linked gene in leukemia susceptibility.
|
12002748 |
2002 |
rs1275561861
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Its male-specificity, occurrence in childhood and the lack of a gene-dosage effect suggest that the C282Y association in childhood ALL may reflect the involvement of another HLA-linked gene in leukemia susceptibility.
|
12002748 |
2002 |
rs387906553
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Collectively, these data suggest that expression of V72M NE is not sufficient to induce an SCN phenotype or leukemia in mice.
|
12384420 |
2002 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate.
|
12453860 |
2002 |
rs762613037
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The bone marrow and/or peripheral blood from 126 patients with acute myeloid leukemia (AML), 57 with chronic myeloid leukemia (CML), 91 with acute lymphocytic leukemia (ALL), and 178 normal controls were analyzed using a polymerase chain reaction-restriction fragment length polymorphism (RFLP) assay to evaluate the association of the endostatin polymorphisms D104N (nucleotide 4349G --> A) with leukemia.
|
12693719 |
2003 |
rs11547328
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors.
|
12731669 |
2003 |
rs771138120
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors.
|
12731669 |
2003 |
rs121912438
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The effect of leukaemia inhibitory factor on SOD1 G93A murine amyotrophic lateral sclerosis.
|
12967646 |
2004 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our results suggest that the MTHFR C677T polymorphism displays a similar distribution pattern in lymphoid and myeloid leukemias and that the frequency of the homozygote variant genotype (677TT) is lower in all leukemia types.
|
15068389 |
2003 |
rs121913459
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The resistance to the tyrosine kinase inhibitor imatinib in BCR/ABL-positive leukemias is mostly associated with mutations in the kinase domain of BCR/ABL, which include the most prevalent mutations E255K and T315I.
|
15194504 |
2004 |
rs1360131632
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The resistance to the tyrosine kinase inhibitor imatinib in BCR/ABL-positive leukemias is mostly associated with mutations in the kinase domain of BCR/ABL, which include the most prevalent mutations E255K and T315I.
|
15194504 |
2004 |
rs121913448
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The resistance to the tyrosine kinase inhibitor imatinib in BCR/ABL-positive leukemias is mostly associated with mutations in the kinase domain of BCR/ABL, which include the most prevalent mutations E255K and T315I.
|
15194504 |
2004 |