Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs755009196
rs755009196
ATM ; C11orf65
G 0.700 GeneticVariation CLINVAR

dbSNP: rs121913615
rs121913615
MPL
0.010 GeneticVariation BEFREE Retrospective molecular studies detected a MPL W515S homozygous mutation in both the initial and remission marrows for B-ALL, at 30-40% and 80% dosage effect, respectively. 25453399

2015
dbSNP: rs2032582
rs2032582
ABCB1
0.010 GeneticVariation BEFREE In the subgroup analysis, according to the type of leukemia, significant association was found between MDR1 G2677T polymorphism and myeloid leukemia but not lymphoblastic leukemia (TT vs. GG: OR = 0.66, 95% CI = 0.46-0.95, P = 0.026; TT vs. 24142546

2014
dbSNP: rs121913514
rs121913514
KIT
0.010 GeneticVariation BEFREE In mice, HyC-KIT N822K induced a myeloproliferative disease, whereas HyC-KIT 571+14 induces both myeloproliferative disease and lymphocytic leukemia. 21262832

2011