|
rs3731217
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Here, we conducted a systematic review and meta-analysis to re-evaluate the association of both SNPs (rs3731217 and rs3731249) with ALL susceptibility by gathering the data from 24 independent studies, totally containing 7922 cases/21503 controls for rs3731217 and 6295 cases/24191 controls for rs3731249.
|
29654170 |
2018 |
|
rs3731249
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Here, we conducted a systematic review and meta-analysis to re-evaluate the association of both SNPs (rs3731217 and rs3731249) with ALL susceptibility by gathering the data from 24 independent studies, totally containing 7922 cases/21503 controls for rs3731217 and 6295 cases/24191 controls for rs3731249.
|
29654170 |
2018 |
|
rs3731217
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs3731249
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The association between rs3731249 genotype and risk was not specific to particular subtype of B-cell ALL.
|
26463672 |
2015 |
|
rs3731249
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Here we show a missense variant in CDKN2A associated with the development of ALL at genome-wide significance (rs3731249, P=9.4 × 10(-23), odds ratio=2.23).
|
26104880 |
2015 |
|
rs3731217
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblastic leukemia (cases) and 2,398 controls and with validation in samples totaling 2,386 cases and 2,419 controls, we have shown that common variation at 9p21.3 (rs3731217, intron 1 of CDKN2A) influences acute lymphoblastic leukemia risk (odds ratio = 0.71, P = 3.01 x 10(-11)), irrespective of cell lineage.
|
20453839 |
2010 |
|
rs3731246
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The IKZF1 SNPs, rs10235796 and rs6964969, and the CDKN2A SNP rs3731246 (previously unreported) could serve as risk markers for ALL susceptibility in Yemeni children.
|
28768142 |
2017 |